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Medical News Today - Breast Cancer News (30 unread)

• Daily Women's Health Policy Report Summarizes Latest Breast Cancer News

  Posted: January 6th, 2009, 6:00am CST

  The following summarizes recent news coverage related to breast cancer. ~ Genetic testing: NPR's "All Things Considered" on Wednesday profiled members of a family as they decided whether to undergo genetic testing for mutations of the BRCA1 and BRCA2 genes, which are strongly linked to an increased risk of breast and ovarian cancer.

• In Breast Cancers With Poor Prognosis Gene Plays Dual Role

  Posted: January 6th, 2009, 6:00am CST

  A new study reveals that the metadherin gene (MTDH) plays a role in both cancer metastasis and resistance to chemotherapy. The research, published by Cell Press in the January 6th issue of the journal Cancer Cell, identifies MTDH as a promising therapeutic target for high risk breast cancers.

• NYT Examines Challenges To Improving 'Personalized Medicine' For Breast Cancer, Other Diseases

  Posted: January 6th, 2009, 5:00am CST

  The New York Times on Tuesday examined how improvements in genetic testing could affect "personalized medicine" for the treatment of breast cancer and other diseases in the future. Personalized medicine uses genetic screening and other tests to provide physicians with more information to tailor patients' treatments, the Times reports.

• Inflammatory Breast Cancer: A Complex Disease

  Posted: January 6th, 2009, 4:00am CST

  This article reviews the following: "Molecular Determinants of the Inflammatory Breast Cancer Phenotype".

• Team Finds Breast Cancer Gene Linked To Disease Spread

  Posted: January 6th, 2009, 2:00am CST

  A team of researchers at Princeton University and The Cancer Institute of New Jersey has identified a long-sought gene that is fatefully switched on in 30 to 40 percent of all breast cancer patients, spreading the disease, resisting traditional chemotherapies and eventually leading to death.

• Molecular Determinants Of The Inflammatory Breast Cancer Phenotype

  Posted: January 6th, 2009, 2:00am CST

  Despite advances in multimodality treatment, inflammatory breast cancer (IBC) remains the most aggressive and lethal form of breast cancer. The use of primary human IBC cell lines and functional in vivo xenograft cancer models have revealed characteristics innate to IBC thought to confer a strong metastatic potential and aggressive phenotype.

• Gene Helps Breast Cancer Spread And Resist Chemo

  Posted: January 6th, 2009, 2:00am CST

  Scientists in the US looking for genomic changes in breast tumor samples found that a gene called metadherin (MTDH) appears to play a dual role in both helping cancer spread (metastasis) and maintain resistance to chemotherapy. They said this research identifies MTDH as an important new target for the treatment of high risk breast cancers.

• Immutep Announces Positive Interim Results In Phase I/II Chemoimmunotherapy Trial In Breast Cancer

  Posted: January 5th, 2009, 7:00am CST

  Immutep S.A. announced today interim results from its ongoing Phase I/II chemoimmunotherapy clinical trial in metastatic breast carcinoma. ImmuFact IMP321 was administered the day after weekly paclitaxel for six months. The interim results show a clinical response rate of 50 per cent compared to 25 per cent with paclitaxel alone. In addition, a robust immune response was observed in clinically-responding patients.

• Cyclophilin B Is A Possible New Target For Treating Breast Cancer

  Posted: January 3rd, 2009, 2:00am CST

  Dr. Charles Clevenger and colleagues at Northwestern University have uncovered that cyclophilin B may contribute to progression in breast cancer. Their report can be found in the January 2009 issue of The American Journal of Pathology. The protein cyclophilin B affects cell division, motility, and death, all of which are altered in cancerous cells. To explore the role of cyclophilin B-mediated gene regulation in breast cancer, Dr.

• UPCI Researcher Receives Grant To Study Breast Cancer Biomarkers

  Posted: January 2nd, 2009, 4:00am CST

  Susan G. Komen for the Cure has awarded Jean Johanna Latimer, Ph.D., assistant professor in the Molecular Genetics and Biochemistry Program at the University of Pittsburgh Cancer Institute (UPCI), a grant to develop biomarkers that will help identify which forms of a common, noninvasive cancer-ductal carcinoma in situ (DCIS)-will metastasize. The research, focusing in part on DCIS in African-American women, may eventually spare patients from unnecessary treatments.

• Medicare Rebate For Breast MRI, Australia

  Posted: January 2nd, 2009, 3:00am CST

  A Medicare rebate for an MRI breast scan will be available to women under 50 at high risk of breast cancer and with no symptoms from 1 February 2009. Being at high risk of breast cancer can cause significant anxiety. These scans can help reduce unnecessary concern, and help pick up breast cancer early.

• MRI Scans Funded For Younger Women At High Risk Of Breast Cancer, Australia

  Posted: December 28th, 2008, 6:00am CST

  National Breast and Ovarian Cancer Centre welcomes the addition of two new items to the Medicare Benefits Schedule (MBS) for the use of Magnetic Resonance Imaging (MRI) in the surveillance and diagnosis of women under 50 years of age at high risk of developing breast cancer.

• New York Times Examines Reconstructive Surgery Options For Women With Breast Cancer

  Posted: December 24th, 2008, 6:00am CST

  The New York Times on Tuesday examined reconstructive breast surgery options provided to cancer patients undergoing mastectomies. According to the Times, despite recent advances in reconstructive breast surgery procedures, many plastic surgeons fail to inform women about the extent of their options.

• Lymphedema Risk For Breast Cancer Survivors Increased By Obesity

  Posted: December 23rd, 2008, 5:00am CST

  Throughout the world, 10 million breast cancer survivors have a lifetime risk for developing lymphedema, a chronic condition that involves swelling of the limbs and impacts physical and psychosocial health. Second only to the recurrence of cancer, it is the most dreaded effect of breast cancer treatment.

• IU Simon Cancer Center's Tissue Bank Collecting Samples Jan. 10

  Posted: December 22nd, 2008, 5:00am CST

  Would you like to contribute to breast cancer research? You can help by donating a tissue sample to the Susan G. Komen for the Cure Tissue Bank at the IU Simon Cancer Center from 8:30 a.m. to 2:30 p.m. Saturday, Jan. 10, in the Hematology Clinic and Women's Center (second floor) in the new patient building of the Indiana University Melvin and Bren Simon Cancer Center, 1030 W. Michigan St.

• Fruit, Veggie Intake Doubled With Switch To Mediterranean Diet Plan

  Posted: December 22nd, 2008, 3:00am CST

  In a new study led by the University of Michigan Health System, women more than doubled their fruit and vegetable intakes and dramatically increased their consumption of "good" fats when they were counseled by registered dietitians and provided with a list of guidelines on the amount of certain foods they should eat each day. The six-month study of 69 women divided the participants into two groups.

• Baby Girl Free Of Breast Cancer Gene Due To Be Born Soon

  Posted: December 21st, 2008, 4:00pm CST

  The first British baby girl free of the faulty BRCA 1 gene, which significantly raises a woman's chances of developing breast cancer, is due to be born soon. The girl has been genetically selected to be free of the faulty gene. As an embryo, she was screened to make sure she did not have the faulty gene. The BRCA 1 gene passes the risk of breast cancer down generations. Experts say a woman who carries this gene runs a 50% to 85% risk of developing breast cancer.

• Extra-Virgin Olive Oil Has Anti-Cancer Components

  Posted: December 20th, 2008, 6:00am CST

  Good quality extra-virgin olive oil contains health-relevant chemicals, 'phytochemicals', that can trigger cancer cell death. New research published in the open access journal BMC Cancer sheds more light on the suspected association between olive oil-rich Mediterranean diets and reductions in breast cancer risk.

• 'Molecular Manual' For 100s Of Inherited Diseases Compiled By Researchers

  Posted: December 20th, 2008, 3:00am CST

  An international research team has compiled the first catalogue of tissue-specific pathologies underlying hundreds of inherited diseases. These results provide information that may help treat conditions such as breast cancer, Parkinson's disease, heart disease and autism. The report from scientists at the Technical University of Denmark and Massachusetts General Hospital (MGH) will appear in the Proceedings of the National Academy of Sciences and has been published online.

• Breast Cancer Recovery Hampered By Poor Marriage

  Posted: December 19th, 2008, 6:00am CST

  Researchers in the US found that breast cancer patients who had a poor relationship with their spouse or partner were likely to recover more slowly and experience worse physiological as well as psychological outcomes.

• Daily Women's Health Policy Report Examines Latest Research On Breast Cancer

  Posted: December 18th, 2008, 8:00am CST

  The following summarizes news coverage of recently reported studies on breast cancer. ~ Tumor removal: An experimental device developed by a team at Duke University Medical Center can help surgeons determine if they have removed a breast cancer tumor in its entirety, reducing the chances that a patient will have to undergo subsequent surgeries, researchers reported at the recent

• Cabinet Secretary For Health & Wellbeing Hears Breast Cancer Patient Experiences At Breakthrough Breast Cancer's Scottish Launch Event

  Posted: December 18th, 2008, 6:00am CST

  Nicola Sturgeon, MSP and Deputy First Minister & Cabinet Secretary for Health & Wellbeing heard breast cancer patients talk about their experiences of breast cancer services in Scotland at Breakthrough Breast Cancer's Scottish Conversation event on Wednesday 10th December.

• Ovarian, Breast And Lung Cancer Survival Linked To Two Proteins

  Posted: December 18th, 2008, 6:00am CST

  US scientists found that levels of two proteins called Dicer and Drosher that are involved in shutting down genes were linked to a woman's chances of surviving ovarian cancer and similar effects were also found in lung and breast cancer patients. Women with high levels of these proteins had a median survival of 11 years while women with low levels of both proteins only had a median survival rate of 2.7 years.

• ERMA's Ban On The Use Of Endosulfan A Significant Step Forward For New Zealand Women

  Posted: December 18th, 2008, 4:00am CST

  Breast Cancer Network NZ is delighted that ERMA has decided to ban the pesticide endosulfan in New Zealand. This chemical is acutely toxic and has hormone-mimicking qualities that are of great concern to Breast Cancer Network. Early exposure of our children and young people to endocrine-disrupting compounds may play an important role in New Zealand's high incidence of breast cancer.

• Gene Subnetworks Predict Cancer Spread

  Posted: December 18th, 2008, 3:00am CST

  The metastasis or spread of breast cancer to other tissues in the body can be predicted more accurately by examining subnetworks of gene expression patterns in a patient's tumor, than by conventional gene expression microarrays, according to a presentation at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.

• Women With HER2-Positive Breast Cancer Should Be Treated Aggressively, Researchers Report

  Posted: December 17th, 2008, 10:00am CST

  Women with breast cancer who test positive for the HER2 gene -- one of the most aggressive forms of the disease -- should be treated aggressively after surgery, even in cases where present tumors are very small, researchers said Friday at the San Antonio Breast Cancer Symposium, the

• New Research Moves Us One Step Closer To Personalised Breast Cancer Treatment

  Posted: December 17th, 2008, 7:00am CST

  CANCER RESEARCH UK scientists have found that a test, already used in breast cancer diagnosis, can also predict who will and who won't benefit from commonly used chemotherapy drugs. The research shows that women who have a duplication of chromosome 17 in their tumour will benefit from anthracycline drugs, while others can be spared the side-effects of the treatment.

• How Tamoxifen Prevents Breast Cancer In Some Women But Not Others

  Posted: December 17th, 2008, 7:00am CST

  The power of the drug tamoxifen to reduce breast density is key in preventing breast cancer - according to a presentation in America by Cancer Research UK scientists. Researchers monitored the extent to which tamoxifen could reduce breast density in 7000 healthy post menopausal women who are at high risk of breast cancer in a trial called IBIS 1.

• Breast Cancer Recurrence In Women Without Hot Flashes May Be Reduced By Diet

  Posted: December 17th, 2008, 4:00am CST

  A secondary analysis of a large, multicenter clinical trial has shown that a diet loaded with fruits, vegetables and fiber and somewhat lower in fat compared to standard federal dietary recommendations cuts the risk of recurrence in a subgroup of early-stage breast cancer survivors - women who didn't have hot flashes - by approximately 31 percent. These patients typically have higher recurrence and lower survival rates than breast cancer patients who have hot flashes.

• Computer-Aided Mammography Finds More Cancer, More False Positives

  Posted: December 17th, 2008, 3:00am CST

  Computer programs designed to help radiologists could identify more cases of breast cancer, but they might also increase the number of false-positive results, which can lead to biopsies in healthy women, according to a recent systematic review. Using computer-aided detection (CAD) mammography, "you do catch some cases that would have been missed if the mammogram had been read only by a single radiologist," said review author Meredith Noble, a research analyst at ECRI Institute.