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• Study Suggests A Possible Way To Offset Chemobrain Memory Loss

  Posted: September 7th, 2008, 3:00am EDT

  Cancer patients have complained for years about the mental fog known as chemobrain. Now in animal studies at West Virginia University (WVU), researchers have discovered that injections of N-acetyl cysteine (NAC), an antioxidant, can prevent the memory loss that breast cancer chemotherapy drugs sometimes induce. The WVU researchers' study has just been published in the September issue of the Springer journal Metabolic Brain Disease.

• OncoMune Publishes Positive Results Of OCM-8054 - Breast Cancer Dependency On BORIS Unequivocally Demonstrated By RNA Interference

  Posted: September 5th, 2008, 12:00pm EDT

  OncoMune LLC, a biotechnology company focused on developing targeted cancer therapeutics, announced the publication of its preclinical OCM-8054 data. The publication entitled, "Selective apoptosis of breast cancer cells by siRNA targeting of BORIS," appeared in the May 23rd 2008 issue of the scientific journal, Biochemical and Biophysical Research Communications, Volume 370, Issue 1, Pages 109-112.

• Black Women Less Likely Than White Women To Receive Follow-Up Treatments After Breast Cancer Surgery, Study Finds

  Posted: September 5th, 2008, 11:00am EDT

  Black women who undergo a lumpectomy surgery to treat early-stage breast cancer are less likely than their white counterparts to receive the recommended follow-up radiation therapy treatments, according to study released on Wednesday, Reuters/Boston Globe reports.

• Agendia Launches TargetPrint(R) For Breast Cancer Patients

  Posted: September 5th, 2008, 7:00am EDT

  Agendia, a world leader in molecular cancer diagnostics, announced the launch of TargetPrint(R), a new diagnostic test that allows physicians to quantitatively determine the gene expression levels of the estrogen receptor (ER), progesterone receptor (PR) and Human Epidermal growth factor Receptor 2 (HER2) in breast cancer tumor biopsies.

• Blacks Less Likely Than Whites To Receive Standard Of Care In Radiation Therapy For Breast Cancer

  Posted: September 5th, 2008, 7:00am EDT

  Black women are less likely than white women to receive radiation therapy after a lumpectomy, the standard of care for early stage breast cancer, according to a new study by researchers at The University of Texas M. D. Anderson Cancer Center. The study, the largest of its kind, was presented in advance of the American Society of Clinical Oncology (ASCO) Breast Cancer Symposium, and is the first national study to examine such racial disparities in radiation therapy.

• Change In HER2 Status After Treatment With Herceptin Discovered By M. D. Anderson Study

  Posted: September 5th, 2008, 7:00am EDT

  Researchers at The University of Texas M. D. Anderson Cancer Center have discovered that when treated with Herceptin prior to surgery, 50 percent of HER2 positive, breast cancer patients showed no signs of disease at the time of surgery. However, of those women who had residual disease, about one-third had tumors that converted from HER2 positive to HER 2 negative status -possibly indicating a resistance to the targeted therapy.

• Wall Street Journal Examines Growing Fear Of Breast Cancer Among Some Young Girls

  Posted: September 4th, 2008, 11:00am EDT

  The Wall Street Journal on Tuesday examined the growing fear of breast cancer among some young girls that in part is because of information about the disease from the media. Marisa Weiss -- director of breast radiation oncology at Lankenau Hospital in Pennsylvania, founder of Breastcancer.

• Olivia Newton-John Partners With Curves To Distribute The Liv(R) Breast Self-Exam Aid To 1 Million Women

  Posted: September 4th, 2008, 6:00am EDT

  Four-time Grammy winner Olivia Newton-John announces a partnership with Curves, the world's largest fitness franchise for women to launch an international campaign to distribute 1 million units of the Liv® Aid, a breast self-exam aid that assists women to exercise breast self-exams correctly.

• IU Simon Cancer Center's Tissue Bank Collecting Samples Sept. 20 At Clarian North

  Posted: September 3rd, 2008, 6:00am EDT

  Would you like to contribute to breast cancer research? You can help by donating a tissue sample to the Susan G. Komen for the Cure Tissue Bank at the IU Simon Cancer Center from 9 a.m. to 2 p.m. Saturday, Sept. 20, at Ology Spa at the Clarian North Medical Center, 11700 North Meridian St., Carmel. A tissue sample will be taken from one breast with a needle and local anesthesia. The amount of tissue taken is about one gram (or the size of two peas).

• Cytokinetics Announces Clinical Trials Data Relating To Ispinesib To Be Presented At The 2008 ASCO Breast Cancer Symposium

  Posted: September 1st, 2008, 4:00am EDT

  Cytokinetics, Incorporated (NASDAQ: CYTK) announced that data from an ongoing Phase I/II clinical trial of ispinesib are scheduled to be presented as a poster presentation at the 2008 American Society of Clinical Oncology (ASCO) Breast Cancer Symposium, to be held September 5-7, 2008 at the Hilton Washington in Washington, DC.

• Growth Factor Predicts Poor Outcome In Breast Cancer

  Posted: September 1st, 2008, 4:00am EDT

  The response to insulin-like growth factor 1 (IGF-I) in breast cancer cells predicts an aggressive tumor that is less likely to respond to treatment, said researchers at Baylor College of Medicine in a report that appears in the current issue of the Journal of Clinical Oncology. The finding gives impetus to the movement to tailor cancer treatments to attributes of the various tumors. "These findings come at a critical time," said Dr.

• FDA Grants IND For Pro-Pharmaceuticals' DAVANAT® To Treat Breast Cancer Patient

  Posted: August 30th, 2008, 5:00am EDT

  Pro-Pharmaceuticals, Inc. (Amex: PRW), today announced that the U.S. Food and Drug Administration (FDA) has granted an Investigational New Drug (IND) application for use of DAVANAT® in combination with 5-FU to treat a breast cancer patient at the Brown Cancer Center in Louisville, Kentucky. DAVANAT® also is being administered in Phase II clinical trials for first-line treatment of colorectal and biliary cancer patients.

• Immigrants From India, Pakistan Face U.S. Prostate, Breast Cancer Risks

  Posted: August 29th, 2008, 7:00am EDT

  A team of researchers at West Virginia University has shown that U.S. immigrants from India and Pakistan take on the habits of their adopted country, increasing their risks of prostate cancer among male immigrants and breast cancer among females. "Breast cancer and prostate cancer develop due to many reasons, but environmental factors and lifestyle play a major role in these cancers," said Jame Abraham, M.D.

• Digital Pathology Leader Adds Third FDA Clearance For Digital Pathology In Breast Cancer

  Posted: August 29th, 2008, 6:00am EDT

  Aperio Technologies, Inc., (Aperio), a global leader in digital pathology for the healthcare and life sciences industry, has received clearance from the U.S. Food and Drug Administration (FDA) to market the ER and PR image analysis applications available through its patented ScanScope® slide scanning system.

• PresGar Implements RamSoft's Digital Mammography Software

  Posted: August 29th, 2008, 4:00am EDT

  Less than a year into the process, RamSoft, a leading developer of affordable healthcare information technology, has successfully helped PresGar, the nation's largest privately-owned medical imaging service company, establish a significant digital mammography presence at eight of its imaging centers. The result has been increased efficiency among PresGar mammographers and technologists and substantial savings for the company.

• Breakthrough's Comment On Research Suggesting Positive Or Negative Experiences Can Affect Breast Cancer Risk

  Posted: August 28th, 2008, 6:00am EDT

  Research published in BMC Cancer suggests that positive thinking can reduce the risk of breast cancer, while negative experiences may increase risk. Dr Sarah Cant, Policy Manager at Breakthrough Breast Cancer, says: "There is no clear evidence that positive or negative experiences can affect breast cancer risk. Emotional stress is highly subjective and is difficult to measure accurately.

• Breastfeeding Could Reduce Risk Of Aggressive Form Of Breast Cancer That Disproportionately Affects Black, Younger Women

  Posted: August 27th, 2008, 12:00pm EDT

  Breastfeeding for at least six months might lower the risk of developing so-called "triple negative" breast cancer, an aggressive form of the disease that is more common in black and younger women, according to a study published on Monday in the journal Cancer, the Seattle Post-Intelligencer reports (Paulson, Seattle Post-Intelligencer, 8/24).

• New Target For Fight Against Common Type Of Breast Cancer: Brk

  Posted: August 27th, 2008, 6:00am EDT

  A new promising enzyme target for a specific type of breast cancer, Brk, has been identified in research published on August 21, 2008 in the Proceedings of the National Academy of Sciences (PNAS.) In a specific subset of breast cancer patients, the tumor cells produce high levels of the protein ErbB2 (also called HER2) which pushes the cells to proliferate without limit, a characteristic common of all cancers.

• American Medical Student Association Academy Provides Leadership Training For Tomorrow's Physicians

  Posted: August 27th, 2008, 4:00am EDT

  The American Medical Student Association (AMSA), the nation's oldest and largest, independent association for physicians-in-training, announces the commencement of AMSA Academy, a training ground for physician leaders. Established by students, for students, AMSA Academy takes medical students through the core competencies of leadership and project implementation, while building on key principles of important topics in medicine. There are currently 22 programs offered.

• Greater Risk Of Breast Cancer In Women Exposed To Negative Life Events

  Posted: August 26th, 2008, 4:00am EDT

  Happiness and optimism may play a role against breast cancer while adverse life events can increase the risk of developing the disease, according to a study by Professor Ronit Peled, at Ben-Gurion University of the Negev in Israel. An article on the study titled "Breast Cancer, Psychological Distress and Life Events among Young Women," was just published in the British journal BMC Cancer (8:245, August 2008).

• Positive Thinking May Protect Against Breast Cancer

  Posted: August 25th, 2008, 5:00am EDT

  Feelings of happiness and optimism play a positive role against breast cancer. Research published in the open access journal BMC Cancer suggests that while staying positive has a protective role, adverse life events such as the loss of a parent or close relative, divorce or the loss of a spouse can increase a woman's risk of developing the disease.

• Dense Breast Tissue Promotes Aggressive Cancers

  Posted: August 25th, 2008, 4:00am EDT

  New research may explain why breast cancer tends to be more aggressive in women with denser breast tissue. Breast cancer cells grown in dense, rigid surroundings step up their invasive activities, Vanderbilt-Ingram Cancer Center investigators report in the Sept. 9 issue of Current Biology. The findings suggest a cellular mechanism for the correlation between human breast tissue density and tumor aggressiveness.

• Inhibiting 2 Pathways Rather Than 1 Enhances Anti-Tumor Effects

  Posted: August 24th, 2008, 4:00am EDT

  Two independent research groups have found that simultaneous inhibition of two signaling pathways resulted in substantially enhanced antitumor effects in mouse models of prostate and breast cancer. In an accompany commentary, Steven Grant, at Virginia Commonwealth University Health Science Center, Richmond, discusses the clinical importance of these studies and highlights some of the questions that still need to be answered.

• HRT Improves Quality Of Life For Some

  Posted: August 23rd, 2008, 3:00am EDT

  A new study published on bmj.com argues that for older women, health related quality of life can be improved by hormone replacement therapy (HRT). The authors recommend that HRT guidelines should be revised with this most current evidence taken into consideration. Earlier studies have shown that HRT has the potential for general improvements in quality of life measures - how patients feel or function.

• Duke Chemists Synthesize Promising Anti-cancer Product

  Posted: August 22nd, 2008, 4:00am EDT

  Duke University chemists have patented an efficient technique for synthesizing a marine algae extract in sufficient quantities to now test its ability to inhibit the growth of cancerous cells while leaving normal cells unaffected. The researchers also deduced that this molecule -- called largazole -- acts on cells through the same chemical mechanism as other anti-cancer compounds on the market or in clinical trials.

• Synthetic Molecules Could Add Spice To Fight Against Cancer

  Posted: August 19th, 2008, 4:00am EDT

  Seeking to improve on nature, scientists used a spice-based compound as a starting point and developed synthetic molecules that, in lab settings, are able to kill cancer cells and stop the cells from spreading. The researchers are combining organic chemistry, computer-aided design and molecular biology techniques in developing and testing pharmaceutical compounds that can fight breast and prostate cancer cells.

• Global Phase 3 Study Of IMC-1121B In Metastatic Breast Cancer Commences

  Posted: August 18th, 2008, 5:00am EDT

  ImClone Systems Incorporated (NASDAQ: IMCL), a global leader in the development and commercialization of novel antibodies to treat cancer, today announced that the first patient has been treated in a global Phase 3 clinical trial of IMC-1121B, its anti-vascular endothelial growth factor receptor-2 (VEGFR-2) IgG1 monoclonal antibody, in women with metastatic breast cancer.

• Breast Cancer Patient Advocates Concerned About Relationship With Genentech If Acquired By Roche

  Posted: August 18th, 2008, 3:00am EDT

  Advocates, including those for breast cancer patients, are concerned about their relationship with pharmaceutical company Genentech following Roche's bid for the company, the

• Breast Cancer Patient Advocates Concerned About Relationship With Genentech If Acquired By Roche

  Posted: August 18th, 2008, 3:00am EDT

  Advocates, including those for breast cancer patients, are concerned about their relationship with pharmaceutical company Genentech following Roche's bid for the company, the

• Nebraska Women Benefit From Efforts To Close Gaps In Cancer Screening

  Posted: August 16th, 2008, 4:00am EDT

  A decade-long Nebraska study that showed disparities in breast and cervical cancer screenings could have spurred changes that raised the percentage of women screened in the state. "Disparities in screening between racial and ethnic groups, even in a homogeneous state such as Nebraska, are a problem and by digging into some of the differences we were able to have an impact on breast and cervical cancer screening," said lead study author Shingairai Feresu, Ph.D.