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Breast Cancer Drug Exemestane Causes Substantial Bone Loss
Posted: February 6th, 2012, 8:00pm CST
A recent study published in The Lancet Oncology shows how exemestane (Aromasin), a drug that prevents the development of breast cancer in postmenopausal women, may significantly worsen age-related bone loss. As an aromatase inhibitor, exemestane works by blocking the synthesis of estrogen, slowing down the growth of cancers that have estrogen receptors... -
Has Komen Shot Itself In The Foot?
Posted: February 5th, 2012, 4:00pm CST
Susan G. Komen for the Cure, a breast cancer charity which until recently had an enviable reputation as being totally impartial and focused purely on saving women's lives, may have caused itself irreparable damage. By announcing a few days ago that it would stop awarding funds to Planned Parenthood, a sexual health organization; it found itself in the middle of an enormous public outcry... -
Battling Lung Cancer With Combination Drug Therapy
Posted: February 5th, 2012, 2:00am CST
Combination drug therapy may be needed to combat non-small cell lung cancer (NSCLC), according to a study by the Translational Genomics Research Institute (TGen) and Van Andel Research Institute (VARI). The study, "STAT3 is Activated by JAK2 Independent of Key Oncogenic Driver Mutation in Non-Small Cell Lung Carcinoma," was published online by the Public Library of Science (PLoS) ONE... -
Partial Mastectomies Often Result In Further Surgeries
Posted: February 3rd, 2012, 1:00pm CST
According to an investigation in the February 1 issue of JAMA, surgery to remove additional tissue (reexcision) is required in almost 1 in 4 women who undergo a partial mastectomy for breast cancer treatment. In addition, there is considerable surgeon and institutional difference in the rate of reexcisions that have nothing to do with patients' characteristics. In the U.S... -
Protein Structures Offer Clues To Breast Cancer, Alzheimer's Treatment, Prevention
Posted: February 3rd, 2012, 3:00am CST
Using some of the most powerful nuclear magnetic resonance equipment available, researchers at the University of California, Davis, are making discoveries about the shape and structure of biological molecules - potentially leading to new ways to treat or prevent diseases such as breast cancer and Alzheimer's disease... -
Cancer Genomics: Special Issue Published By Genome Research
Posted: February 3rd, 2012, 3:00am CST
Genome Research publishes online and in print a special issue entitled, "Cancer Genomics," highlighting insights gained form cutting-edge genomic and epigenomic analyses of cancer... -
Study Suggests Surgical Breast Biopsy Not Overused
Posted: February 3rd, 2012, 2:00am CST
Contrary to earlier findings, surgical breast biopsies may not be as overused as previously thought, according to a study in the February issue of the Journal of the American College of Radiology. Surgical breast biopsies are more invasive than needle biopsies, requiring an incision and the use of general anesthesia... -
Dropping Planned Parenthood Is Not Political, Says Susan G. Komen For The Cure
Posted: February 2nd, 2012, 11:00am CST
Breast cancer charity, Susan G. Komen for the Cure, says that dropping Planned Parenthood from its granting process is not political, and says it is "dismayed and extremely disappointed" that its action has been mischaracterized. The charity says it has taken actions to make its granting process stronger and more effective, resulting in Planned Parenthood being dropped from its list of grantees... -
Recommended Breast Screening MRI Not Followed Through
Posted: February 2nd, 2012, 3:00am CST
A study of 64,659 women, recently published in the journal Academic Radiology, found that while 1,246 of these women were at high enough breast cancer risk to recommend additional screening with MRI, only 173 of these women returned to the clinic within a year for the additional screening... -
Breast Cancer Surgery Often Repeated To Take Out More Tissue
Posted: February 1st, 2012, 1:00pm CST
22.9% of breast cancer patients who undergo partial mastectomies need further operations to remove more tissue, researchers reported in JAMA (Journal of the American Medical Association)... -
Accuracy Of Mammogram Readings Improved With Visual Nudge
Posted: January 30th, 2012, 2:00am CST
In 2011 - to the consternation of women everywhere - a systematic review of randomized clinical trials showed that routine mammography was of little value to younger women at average or low risk of breast cancer... -
Discovery Of Rotational Motion Of Cells That Plays A Critical Role In Their Normal Development Has Major Implications For Breast Cancer Research
Posted: January 29th, 2012, 2:00am CST
In a study that holds major implications for breast cancer research as well as basic cell biology, scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) have discovered a rotational motion that plays a critical role in the ability of breast cells to form the spherical structures in the mammary gland known as acini... -
Cancer Screening Rates Low Among Ethnic Groups, USA
Posted: January 27th, 2012, 12:00pm CST
Not only are relatively few Americans screened for cancer, but there are considerable disparities between ethnic and racial groups in the country, says a new report issued by NCI (National Cancer Institute) and the CDCF (Centers for Disease Control and Prevention). The authors added that screening rates are especially low among Hispanic and Asian Americans... -
Breast Cancer Tissue Bank Opens To All, UK
Posted: January 26th, 2012, 6:00pm CST
The first national breast cancer tissue bank in the UK has opened its vaults of precious breast cancer tissue to all researchers in the UK and Ireland, providing a massive boost to breast cancer research. The bank is a unique collaboration of four leading research institutions and the NHS... -
Breast Cancer Survival - Why Avastin And Sutent Don't Help
Posted: January 26th, 2012, 6:00am CST
Avastin and Sutent, two cancer drugs, do not lead to longer survival in breast cancer patients, probably because they encourage an increase in the number cancer stem cells in breast tumors, according to a study carried out on mice by researchers from the Michigan Comprehensive Cancer Center, and published in the Proceedings of the National Academy of Sciences (early edition)... -
Musculoskeletal Side Effects From Breast Cancer Treatment Are Not Long Term
Posted: January 24th, 2012, 12:00pm CST
Around 75% of the 48,000 women annually diagnosed with breast cancer in the UK suffer from an estrogen receptor positive tumor, which implies the involvement of the hormone estrogen in cancer growth... -
Breast Cancers And Leukemias Slowed By A Single Therapy
Posted: January 24th, 2012, 5:00am CST
Targeting a single protein can help fight both breast cancers and leukemias, according to two reports published online in the Journal of Experimental Medicine. The single protein is HSP90, which acts as a chaperone to protect other proteins in the cell... -
The Genome And The Timing Of Menopause
Posted: January 24th, 2012, 4:00am CST
An international team of researchers has discovered 13 new regions of the genome associated with the timing of menopause. These genes shed light on the biological pathways involved in reproductive lifespan and will provide insights into conditions connected to menopause, such as breast cancer and heart disease... -
In Breast Cancer, The Quality Of Life For Younger Patients More Adversely Affected Than For Older Women
Posted: January 24th, 2012, 4:00am CST
Quality of life in younger patients treated for breast cancer is seriously compromised and these women suffer from severe psychological distress, infertility, premature menopause, a decrease in physical activity and weight gain, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center... -
More Adverse Quality-Of-Life Issues Experienced By Younger Breast Cancer Patients
Posted: January 24th, 2012, 2:00am CST
Younger women with breast cancer experience a decrease in their health-related quality of life (QOL), associated with increased psychological distress, weight gain, a decline in their physical activity, infertility and early onset menopause, according to a study published in the Journal of the National Cancer Institute... -
Lower Quality Of Life In Young Women With Breast Cancer
Posted: January 23rd, 2012, 12:00pm CST
A study in the Journal of the National Cancer Institute reveals that health-related quality of life (QOL) is lower in younger women with breast cancer. This decrease is linked to weight gain, increased psychological distress, less physical activity and early onset menopause, as well as infertility. In the U.S... -
Statins May Work Against Certain Breast Cancers
Posted: January 23rd, 2012, 4:00am CST
Statins are commonly prescribed to lower cholesterol, but a recent study suggest certain types of breast cancer may respond to treatment with statins... -
Red Wine Versus White Wine - Comparison Of Effects On Hormones Related To Breast Cancer Risk
Posted: January 22nd, 2012, 2:00am CST
Aromatase inhibitors (AIs) prevent the conversion of androgens to estrogens, and could play a role in the development of breast cancer. This study of 36 pre-menopausal women consisted of a cross-over intervention trial to determine if there were differences between red wine and white wine in their effects on AIs... -
Cholesterol-Lowering Statins May Treat Breast Cancer
Posted: January 21st, 2012, 2:00am CST
Cholesterol-lowering statins seem to keep breast cancer at bay in some patients. Now researchers reporting in the January 20th issue of the journal Cell, a Cell Press publication, provide clues about how statins might yield those unexpected benefits. The findings also suggest that mutations in a single gene could be used to identify tumors likely to respond to statin therapy... -
Tykerb And Herceptin - Their Role In Breast Cancer Treatment Clarified
Posted: January 19th, 2012, 10:00am CST
Patients with HER2-positive breast cancer have been treated with Tykerb (lapatinib) both in combination with herceptin (trastuzumab), and as an alternative single-agent therapy for pre-surgery (neo-adjuvant) chemotherapy... -
Scriptaid Revives Breast Cancer Treatment Receptivity
Posted: January 18th, 2012, 12:00pm CST
A study by researchers from the Sbarro Institute for Cancer Research and Molecular Medicine, reveals that despite the effectiveness of endocrine therapy for breast cancer, responsiveness to the treatment depends on expression of estrogen receptors in breast cancer cells. However, Dr... -
A Protein May Trigger Spread Of Breast Cancer
Posted: January 18th, 2012, 2:00am CST
Cancers rarely are deadly unless they evolve the ability to grow beyond the tissues in which they first arise. Normally, cells - even early-stage tumor cells - are tethered to scaffolding that helps to restrain any destructive tendencies... -
Researchers Identify Changes In Tumor Cells That Lead To Metastasis
Posted: January 18th, 2012, 2:00am CST
Researchers at the Centro de Gen0mica e Investigaci0n Oncologica (GENYO) - of which the University of Granada, Pfizer and the Andalusian Regional Government are members - have identified the genetic and phenotypic changes that cause tumor progression and metastasis... -
Preoperative Breast Cancer Treatment May Be Improved By Combining 2 Anti-HER2 Drugs
Posted: January 17th, 2012, 4:00am CST
Using two drugs that inhibit the growth factor HER2 for preoperative treatment of early-stage HER2-positive breast cancer appears to have better results than treatment with a single agent... -
Possible Receptor For Key Breast Cancer Regulator Identified By Researchers
Posted: January 16th, 2012, 2:00am CST
A key protein potentially involved in regulating breast cancer progression has been identified by researchers at Clarkson University in Potsdam, N.Y. Led by professor Costel Darie, the team worked to identify the binding partner of Tumor Differentiating Factor (TDF), a pituitary hormone that had previously been shown to reduce cancer progression in breast cancer cells... -
New, Noninvasive Way To Identify Lymph Node Metastasis
Posted: January 15th, 2012, 2:00am CST
Using two cell surface markers found to be highly expressed in breast cancer lymph node metastases, researchers at Moffitt Cancer Center, working with colleagues at other institutions, have developed targeted, fluorescent molecular imaging probes that can non-invasively detect breast cancer lymph node metastases... -
Deodorant Preservative Found In Breast Tissue From Cancer Patients
Posted: January 13th, 2012, 5:00pm CST
A new study led by the University of Reading in the UK that examined breast tissue samples from 40 women who underwent mastectomies for breast cancer, found they contained widespread traces of parabens, preservatives commonly used in deodorants, make-up, body lotions, moisturisers and many other cosmetic products... -
Discovery Of Novel Therapeutic Target To Slow Breast Cancer Cell Motility
Posted: January 13th, 2012, 3:00am CST
Interferon-stimulated gene 15 (ISG15), a ubiquitin like protein, is highly elevated in a variety of cancers including breast cancer. How the elevated ISG15 pathway contributes to tumorigenic phenotypes remains unclear and is the subject of a study published in the January 2012 issue of Experimental Biology and Medicine. Dr... -
Further Investigation Needed To Understand Link Between Parabens And Breast Cancer
Posted: January 13th, 2012, 2:00am CST
New research into the potential link between parabens and breast cancer has found traces of the chemicals in breast tissue samples from all of the women in the study. Parabens are commonly used as preservatives in cosmetics, food products and pharmaceuticals... -
A Plan To Effectively Treat Psoriasis
Posted: January 12th, 2012, 3:00am CST
About 300 000 Swedes suffer from the difficult to treat disease, which manifests itself in scaly and often itchy patches on the skin. The reason is that cells divide without restraint as new blood vessels form in the deeper layers of the skin. An important component is the psoriasin protein (S100A7), which are abundant in psoriasis-affected skin but rarely in normal skin... -
Study Reveals Need For Improvements In Decision-Making Process For Breast Cancer Surgery Patients
Posted: January 12th, 2012, 2:00am CST
According to the results of a new study published in the January 2012 issue of the Journal of the American College of Surgeons, many early-stage breast cancer survivors lacked knowledge about their disease and were not meaningfully involved in treatment discussions or asked their preferences regarding the approach to treatment... -
How Obesity Affects Cancer Screening
Posted: January 11th, 2012, 2:00am CST
Researchers in Family and Community Medicine at Thomas Jefferson University recently found that obesity was linked to higher rates of prostate cancer screening across all races/ethnic differences and lower rates of cervical cancer screening, most notably in white women... -
Sharing Breast Cancer Results With Children Is Popular
Posted: January 10th, 2012, 12:00pm CST
An investigation published online in CANCER, a peer-reviewed journal of the American Cancer Society has discovered that many parents share their breast cancer test results with their children, even if they are very young. Furthermore, the researchers discovered that the majority of parents believe that their children are not distressed when they find out about the test results... -
Following Genetic Testing For Breast Cancer Genes, Most Parents Share Results With Their Children
Posted: January 10th, 2012, 5:00am CST
A new study has found that when parents get tested for breast cancer genes, many of them share their results with their children, even with those who are very young. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study also revealed that most parents think that their children are not distressed when they learn about the test results... -
Lung Cancer Prevention Potential For Estrogen-Targeting Drug Combo
Posted: January 10th, 2012, 3:00am CST
A combination of drugs that target estrogen production significantly reduced the number of tobacco carcinogen-induced lung tumors in mice, according to results from a preclinical study. "Antiestrogens have been shown to prevent breast cancer in some women," said Jill M. Siegfried, Ph.D... -
Researchers Find Malignancy-Risk Gene Signature For Early-Stage Non-Small Cell Lung Cancer
Posted: January 10th, 2012, 2:00am CST
A malignancy-risk gene signature developed for breast cancer has been found to have predictive and prognostic value for patients with early stage non-small cell lung cancer. The advancement was made by researchers at Moffitt Cancer Center in Tampa, Fla., who published their study results in a recent issue of the Journal of the National Cancer Institute... -
Significant Cost Savings Associated With Emergence Of Prospective Surveillance Model As Standard Of Care For Breast Cancer Treatment
Posted: January 9th, 2012, 2:00am CST
Early diagnosis and treatment of breast cancer-related lymphedema by a physical therapist can significantly reduce costs and the need for intensive rehabilitation, according to an article published in the January issue of Physical Therapy (PTJ), the scientific journal of the American Physical Therapy Association (APTA)... -
Cell-CT: A New Dimension In Breast Cancer Research
Posted: January 8th, 2012, 2:00am CST
Despite advances in both the diagnosis and treatment of breast cancer, the disease remains a leading worldwide health concern... -
Red Wine Reduces Breast Cancer Risk
Posted: January 7th, 2012, 2:00am CST
Regular alcohol consumption raises breast cancer risk, except for red wine, which has the opposite effect when consumed in moderation, researchers from Cedars-Sinai Medical Center in Los Angeles reported in the Journal of Women's Health... -
Antiestrogen Therapy May Decrease Risk For Melanoma
Posted: January 6th, 2012, 2:00am CST
Women with breast cancer who take antiestrogen supplements may be decreasing their risk for melanoma, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research. Christine Bouchardy, M.D., Ph.D... -
Researchers Discover Trigger For Breast Cancer Spread
Posted: January 5th, 2012, 3:00am CST
Research led by Shyamal Desai, PhD, Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, has discovered a key change in the body's defense system that increases the potential for breast cancer to spread to other parts of the body. The results, reported for the first time, are featured in the January 2012 issue of Experimental Biology and Medicine... -
Mindfulness-Based Stress Reduction Benefits Breast Cancer Survivors
Posted: January 4th, 2012, 2:00am CST
Women recently diagnosed with breast cancer have higher survival rates than those diagnosed in previous decades, according to the American Cancer Society. However, survivors continue to face health challenges after their treatments end. Previous research reports as many as 50 percent of breast cancer survivors are depressed... -
State Will Pay For PIP Breast Implant Removal, Says Venezuelan Health Minister
Posted: December 28th, 2011, 1:00pm CST
Venezuelan Health Minister, Eugenia Sader, has announced that the full costs of removing the Poly Implant Prothèses (PIP) breast implants will be covered by the state. Ms. Sader emphasized that this offer stands for any woman who wishes to have them removed. French authorities have also offered to cover the full costs... -
Researchers Present Findings From Kentucky Breast Cancer Patients With Disease Relapse
Posted: December 24th, 2011, 3:00am CST
The University of Kentucky Markey Cancer Center breast oncologist Dr. Suleiman Massarweh and his research team presented findings from their studies on relapse of breast cancer at the San Antonio Breast Cancer Symposium this month. The two studies aimed to characterize further risk factors for presentation with metastatic disease or risk of early metastatic relapse after initial therapy... -
Beast Cancer - Patients Prefer It When Specialists Share Care Management
Posted: December 22nd, 2011, 12:00pm CST
According to a novel investigation in Health Services Research, greater satisfaction is reported among individuals with breast cancer when their doctor co-manages their care with other specialists. Although, some specialists are more likely to share decision-making with other physicians. Katherine Kahn, M.D...