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• Early And Accurate Detection Of Bowel Cancer With RanplexCRC - Detects 28 Polymorphisms Associated With Colorectal Cancer In A Single Stool Sample

  Posted: September 7th, 2008, 3:00am EDT

  RanplexCRC is a diagnostic test that can detect 28 polymorphisms associated with colorectal cancer in a single stool sample. It does not require a hospital visit or dietary restrictions, while having greater sensitivity than the currently used Faecal Occult Blood (FOB) screening test. RanplexCRC may more accurately profile patients and reduce the number of patients for colonoscopy, saving time and resources and reducing patient discomfort.

• An Advance On New Generations Of Chemotherapy And Antiviral Drugs

  Posted: September 7th, 2008, 3:00am EDT

  Researchers are describing progress toward developing a new generation of chemotherapy agents that target and block uncontrolled DNA replication - a hallmark of cancer, viral infections, and other diseases - more effectively than current drugs in ways that may produce fewer side effects. Their article is scheduled for the Aug. 27 issue of ACS' Biochemistry, a weekly journal. In the article, Anthony J.

• Study Suggests A Possible Way To Offset Chemobrain Memory Loss

  Posted: September 7th, 2008, 3:00am EDT

  Cancer patients have complained for years about the mental fog known as chemobrain. Now in animal studies at West Virginia University (WVU), researchers have discovered that injections of N-acetyl cysteine (NAC), an antioxidant, can prevent the memory loss that breast cancer chemotherapy drugs sometimes induce. The WVU researchers' study has just been published in the September issue of the Springer journal Metabolic Brain Disease.

• First Day Of Ovarian Cancer Symposium Focuses On Early Detection - Ovarian Cancer Research Symposium

  Posted: September 6th, 2008, 10:00am EDT

  Leading ovarian cancer researchers and clinicians from around the world gathered at the Ovarian Cancer Research Symposium today to hear about cutting-edge developments that may increase the chances of early detection of the disease. Dr. Patricia Kruk, from the University of South Florida, presented her research that could lead to using a non-invasive urine test for detecting ovarian cancer.

• Elan And Biogen Idec Initiate First Clinical Trial Of TYSABRI(R) In Oncology - First Multiple Myeloma Patient Treated

  Posted: September 6th, 2008, 8:00am EDT

  Elan Corporation, plc (NYSE: ELN) and Biogen Idec (NASDAQ: BIIB) announced the initiation of the first clinical trial of TYSABRI® (natalizumab) in oncology. The first dose of TYSABRI was administered yesterday in the trial. The objectives of this Phase I/II study are to evaluate the safety and potential anti-tumor activity of TYSABRI in patients with relapsed or refractory multiple myeloma.

• Amrubicin Receives FDA Fast Track Designation For The Treatment Of Small Cell Lung Cancer After First-Line Chemotherapy

  Posted: September 6th, 2008, 5:00am EDT

  Celgene Corporation (NASDAQ: CELG) announced that Amrubicin has been granted Fast Track product designation by the U.S. Food and Drug Administration (FDA) for the treatment of small cell lung cancer after first-line chemotherapy.

• After A Liver Operation, African-Americans At Twice The Risk Of Death As Caucasians

  Posted: September 6th, 2008, 4:00am EDT

  New research published in the Journal of the American College of Surgeons shows African Americans are more than twice as likely as Caucasians to die in the hospital after surgical removal of part of the liver -- an increasingly used procedure for the treatment of liver cancer. In recent years, a large body of evidence has emerged revealing significant racial disparities in health care and outcomes in the United States.

• Atomic Structure Of The Mammalian "fatty Acid Factory" Determined

  Posted: September 6th, 2008, 4:00am EDT

  Mammalian fatty acid synthase is one of the most complex molecular synthetic machines in human cells. It is also a promising target for the development of anti-cancer and anti-obesity drugs and the treatment of metabolic disorders. Now researchers at ETH Zurich have determined the atomic structure of a mammalian fatty acid synthase. Their results have just been published in Science magazine.

• Unsuccessful Drug Against Anxiety Opens A Novel Gateway For The Treatment Of Cancer

  Posted: September 6th, 2008, 4:00am EDT

  Cancer cells have multiple ways to avoid apoptosis, programmed cell death the means by which organisms deal with defective cells. One defense is to produce quantities of phosphatic acid, a phospholipid constituent of cellular membranes. Unlike other phospholipids, phosphatidic acid also acts as a signaling molecule for cells promoting cellular growth and preventing apoptosis.

• Rosetta Genomics Identifies Potential MicroRNA Biomarkers In Blood Serum

  Posted: September 6th, 2008, 4:00am EDT

  Rosetta Genomics, Ltd. (NASDQ: ROSG), a leader in the development of microRNA-based diagnostic and therapeutic products, announced that the results of a study conducted by its scientists describing the identification of microRNA biomarkers in blood serum, have been published online in the peer-reviewed journal PLOS One. The findings demonstrate that microRNAs have the potential to be used as clinical biomarkers for a wide range of indications in cancer and women's health.

• Pennsylvania Secretary Of Health Stresses Importance Of Cancer Awareness, Education

  Posted: September 6th, 2008, 4:00am EDT

  With the "Stand Up to Cancer" national telethon airing tonight, Secretary of Health Dr. Calvin B. Johnson is reminding Pennsylvanians to educate themselves about cancer and the resources available through the Department of Health. The telethon, aimed at increasing cancer awareness and raising money to support life-saving research, will be carried by the ABC, CBS and NBC networks.

• Vulvar Cancer: A Hidden Disease

  Posted: September 6th, 2008, 4:00am EDT

  Vulvar cancer is the fourth most common cancer of the female genital tract. In 2008, roughly 3,460 cases of vulvar cancer will be diagnosed in the United States and about 870 will die of this cancer, according to the American Cancer Society. There are several different types of vulvar cancer. More than 90 percent are squamous cell carcinomas. Squamous cells are the same kind of cells that comprise most of the skin on the body and the cells that line the inside the body's cavities.

• 25 Years Of Conventional Evaluation Of Data Analysis Proves Worthless In Practice

  Posted: September 6th, 2008, 3:00am EDT

  So-called 'intelligent' computer-based methods for classifying patient samples, for example, have been evaluated with the help of two methods that have completely dominated research for 25 years. Now Swedish researchers at Uppsala University are revealing that this methodology is worthless when it comes to practical problems. The article is published in the journal Pattern Recognition Letters.

• Novel Gateway For The Treatment Of Cancer Opened By Unsuccessful Anxiety Drug

  Posted: September 6th, 2008, 3:00am EDT

  Cancer cells have multiple ways to avoid apoptosis, programmed cell death the means by which organisms deal with defective cells. One defense is to produce quantities of phosphatic acid, a phospholipid constituent of cellular membranes. Unlike other phospholipids, phosphatidic acid also acts as a signaling molecule for cells promoting cellular growth and preventing apoptosis.

• Improved Understanding Of Kidney Diseases

  Posted: September 6th, 2008, 3:00am EDT

  By introducing a genetic switch in mice it is possible to increase or decrease the production of specific protein molecules in their kidneys. Thus, researchers can study the influence of specific proteins on disease development. Scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), Heidelberg University Hospitals and other research institutes have published this model of investigating severe kidney diseases in the latest issue of Nature Medicine.

• More Comprehensive Portrait Of Brain Cancer As A Result Of Collaboration Between Researchers

  Posted: September 6th, 2008, 3:00am EDT

  A team including researchers at the HudsonAlpha Institute and Stanford University, together with colleagues from a number of other organizations, has published a comprehensive analysis of genomic variation in the brain cancer glioblastoma. These results are the first from the Cancer Genome Atlas (TCGA) research network, a collaborative effort funded by the National Cancer Institute and the National Human Genome Research Institute of the National Institutes of Health.

• Discovery of Potential New Targets In Brain Tumors Following Massive Cancer Gene Search

  Posted: September 6th, 2008, 3:00am EDT

  An array of broken, missing, and overactive genes -- some implicated for the first time -- have been identified in a genetic survey of glioblastoma, the most common and deadly form of adult brain cancer, report scientists from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard, together with their collaborating investigators at 18 institutions and organizations.

• Numerous Undiscovered Gene Alterations In Pancreatic And Brain Cancers Revealed

  Posted: September 6th, 2008, 3:00am EDT

  HHMI investigators have detected a multitude of broken, missing, and overactive genes in pancreatic and brain tumors, in the most detailed genetic survey yet of any human tumor. Some of these genetic changes were previously unknown and could provide new leads for improved diagnosis and therapy for these devastating cancers.

• Goshen Center For Cancer Care Doctor Named Naturopathic Physician Of The Year

  Posted: September 5th, 2008, 7:00pm EDT

  Goshen Center for Cancer Care's Director of Integrated Care, Marcia Prenguber, ND, FABNO, has been chosen as the 2008 Naturopathic Physician of the Year by the American Association of Naturopathic Physicians. Dr. Prenguber was honored, and presented with the award, during the AANP's 2008 Annual Convention & Exposition on Aug, 16 at the Arizona Biltmore Resort & Spa in Phoenix, Ariz.

• Discovery Challenges Fundamental Tenet Of Cancer Biology

  Posted: September 5th, 2008, 4:00pm EDT

  Yale researchers have identified an unusual molecular process in normal tissues that causes RNA molecules produced from separate genes to be clipped and stitched together. The discovery that these rearranged products exist in normal as well as cancerous cells potentially complicates the diagnosis of some cancers and raises the possibility that anti-cancer drugs like Gleevec could have predictable side effects. The work is reported in the journal Science.

• Scientists Map Complete Genetic Blueprint Of Deadly Cancers

  Posted: September 5th, 2008, 1:00pm EDT

  In what has been heralded as a significant breakthrough in the fight against two of the world's deadliest cancers, US scientists have mapped complete genetic blueprints comprising more than 20,000 genes in 24 pancreatic cancers and 22 brain cancers, including not only individual gene mutations but also their interlinked pathways which sustain tumour development and growth.

• OncoMune Publishes Positive Results Of OCM-8054 - Breast Cancer Dependency On BORIS Unequivocally Demonstrated By RNA Interference

  Posted: September 5th, 2008, 12:00pm EDT

  OncoMune LLC, a biotechnology company focused on developing targeted cancer therapeutics, announced the publication of its preclinical OCM-8054 data. The publication entitled, "Selective apoptosis of breast cancer cells by siRNA targeting of BORIS," appeared in the May 23rd 2008 issue of the scientific journal, Biochemical and Biophysical Research Communications, Volume 370, Issue 1, Pages 109-112.

• HIV And Prostate Cancer: A Systematic Review Of The Literature

  Posted: September 5th, 2008, 9:00am EDT

  UroToday.com - In the online edition of Prostate Cancer Prostatic Diseases, Dr. Jonathan Silberstein and his colleagues presented a systematic review of HIV and prostate cancer (CaP). The message that may be underappreciated by the urology community is the excellent longevity of HIV patients, which clearly impacts their potential for diagnosis and management of CaP. In 2003, over one-million people were living with HIV in the US and three quarters of them were men.

• September 13th Is National Childhood Cancer Awareness Day

  Posted: September 5th, 2008, 7:00am EDT

  A pediatric bone cancer survivor who now is studying to become a pediatric hematologist/oncologist…a childhood leukemia survivor who has walked a mile in the shoes of the young cancer patients she now treats. These are just a few of the hundreds of patients treated through the Pediatric Hematology/Oncology program at The Cancer Institute of New Jersey (CINJ), which is celebrating 15 years of patient care this year.

• Scientists 'Stand Up To Cancer' With Latest Research

  Posted: September 5th, 2008, 7:00am EDT

  As the Stand Up To Cancer campaign -- being put forth by television's "Big 3" networks -- is opening the nation's eyes to the need and the benefit of cancer research dollars, The Cancer Institute of New Jersey (CINJ) is highlighting some of its groundbreaking studies being conducted by internationally recognized clinical investigators.

• Medarex Announces Presentations At The 33rd Congress Of The European Society For Medical Oncology

  Posted: September 5th, 2008, 6:00am EDT

  Medarex, Inc. (Nasdaq: MEDX) announced that nine clinical abstracts for ipilimumab, an investigational anti-CTLA-4 antibody, in melanoma are scheduled to be the subject of presentations at the 33rd Congress of the European Society for Medical Oncology (ESMO) being held September 12-16, 2008 in Stockholm.

• Azaya Therapeutics Licenses Promising Treatment For Head And Neck Cancers

  Posted: September 5th, 2008, 6:00am EDT

  Azaya Therapeutics, Inc., announced that it has signed a licensing agreement to further develop a breakthrough technology that uses liposomes to deliver radiation through direct injection into head and neck tumors, shrinking the tumor, delaying recurrence and avoiding the collateral tissue damage that often accompanies all other forms of radiation therapy. The company plans to begin a phase I clinical trial in early 2010.

• Nanoscale Droplets With Cancer-Fighting Implications Produced By Scientists

  Posted: September 5th, 2008, 5:00am EDT

  UCLA scientists have succeeded in making unique nanoscale droplets that are much smaller than a human cell and can potentially be used to deliver pharmaceuticals. "What we found that was unexpected was within each oil droplet there was also a water droplet - a double emulsion," said Timothy Deming, professor and chair of the UCLA Department of Bioengineering and a member of both the California NanoSystems Institute (CNSI) at UCLA and UCLA's Jonsson Cancer Center.

• Blood 'Fingerprints' For Cancer

  Posted: September 5th, 2008, 5:00am EDT

  Serum microRNAs (miRNAs) can serve as biomarkers for the detection of diseases including cancer and diabetes, according to research published online this week in Cell Research. The findings pave the way for a revolutionary non-invasive diagnostic tool. miRNAs are a class of naturally occurring small non-coding RNAs that have been linked with cancer development.

• Evident™ Microwave Ablation System Offers Surgical Oncologists And Interventional Radiologists Fast, Efficient Tool To Ablate Soft Tissue

  Posted: September 5th, 2008, 5:00am EDT

  Covidien (NYSE: COV, BSX: COV), a world leader in advanced energy-based surgical systems, today announced the global release of the Evident™ microwave ablation system. Physicians now have a powerful new tool with industry-leading technology to ablate soft tissue. The Evident™ microwave ablation system received 510(k) clearance from the United States Food and Drug Administration for use in soft tissue, and is now the first microwave ablation system available globally.