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Posted: March 31st, 2010, 6:00am CDT
Caudate hepatocellular carcinoma (HCC) has a poorer prognosis than HCC originating from other lobes, due to its proximity to the portal trunk and inferior vena cava, which facilitate intrahepatic and systemic spread early in the disease. Hepatic resection is considered, in principle, to be the first choice treatment...
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Posted: March 31st, 2010, 5:00am CDT
Younger women are likely to attend breast screening if the choice is offered to them, according to the findings of a study of 50,000 women published today in the Journal of Medical Screening...
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Posted: March 31st, 2010, 5:00am CDT
Cancer Research UK announced the launch of three new prestigious awards that will recognise world leading cancer researchers and the scientists of tomorrow. These awards will recognise the contribution and discoveries that thousands of researchers make every day which are helping more people beat the disease...
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Posted: March 31st, 2010, 5:00am CDT
For every woman overdiagnosed by breast screening , two deaths will be prevented, according to a study published today (Wednesday). Following controversial debates in recent months over the risks and harms of screening for breast cancer , the researchers - part funded by Cancer Research UK - set out to uncover how effective the programme is at saving lives...
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Posted: March 31st, 2010, 4:00am CDT
A drug already in clinical trials to treat a variety of tumors shows a remarkable ability to shut down growth of glioblastoma in both laboratory cells and in animals, say researchers from Georgetown Lombardi Comprehensive Cancer Center and the University of California, San Francisco (UCSF)...
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Posted: March 31st, 2010, 4:00am CDT
Following recent controversy about the pros and cons of breast screening, a new study part-funded by Cancer Research UK found that breast screening saves two lives for every case of over-diagnosis. The study by scientists at Wolfson Institute of Preventive Medicine at Barts and the London School of Medicine and Dentistry, is about to be published in the Journal of Medical Screening...
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Posted: March 31st, 2010, 3:00am CDT
Simcere Pharmaceutical Group (NYSE: SCR), a leading manufacturer and supplier of branded generic pharmaceuticals and manufacturer of the patented anti-cancer biotech product Endostar (also known as Endu) in China, announced today the successful completion of Endostar Phase IV clinical study at a conference in Beijing dedicated to this study...
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Posted: March 31st, 2010, 2:00am CDT
Critical Outcome Technologies Inc. (COTI) (TSX VENTURE:COT) announced positive test results today from a series of animal experiments carried out at a prominent Canadian cancer research facility with COTI-2 as a single agent against an aggressive strain of triple negative human breast cancer (TNBC); MDA-MB-231-luc...
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Posted: March 31st, 2010, 1:00am CDT
Pro-Pharmaceuticals, Inc. (OTC: PRWP), a developer of therapeutics that target Galectin receptors to treat cancer and fibrosis, announced that it has granted PROCAPS S.A. exclusive rights to market and sell DAVANAT® to treat cancer in Colombia, South America...
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Posted: March 30th, 2010, 8:00pm CDT
Gemin X Pharmaceuticals, a clinical stage biopharmaceutical company developing novel, targeted cancer therapeutics, today announced the completion of patient enrollment in a Phase 2 clinical trial of the Company's lead product candidate obatoclax (GX15-070) for the treatment of extensive-stage small cell lung cancer (SCLC)...
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Posted: March 30th, 2010, 4:00pm CDT
NexMed, Inc. (NASDAQ: NEXM), a specialty CRO with a pipeline of products based on the NexACT® technology, announced that the Company has filed an Investigational New Drug (IND) application with the U.S...
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Posted: March 30th, 2010, 7:00am CDT
An important gene that normally protects the body against cancer can itself cause a variety of cancers depending on the specific mutation that damages it, according to a new study by investigators at the Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James). The study examined mutations in a gene called PTEN...
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Posted: March 30th, 2010, 7:00am CDT
Preliminary research on cancer treatments using nanotechnology and laser therapy has led to a National Science Foundation (NSF) Faculty Early Career Development (CAREER) award for Marissa Nichole Rylander, Virginia Tech assistant professor jointly appointed in the Department of Mechanical Engineering and Virginia Tech - Wake Forest University School of Biomedical Engineering and Sciences (SBES)...
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Posted: March 30th, 2010, 6:00am CDT
One of the most intriguing questions in cancer research is what causes metastatic tumour migration, why some tumour cells manage to migrate to other parts of the body but others cells don't...
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Posted: March 30th, 2010, 6:00am CDT
Immunovaccine Inc. (TSX VENTURE:IMV) announced that it has started screening patients for its Phase 1 clinical trial, investigating the company's therapeutic cancer vaccine, DPX-0907, as a treatment for patients with advanced stage breast, ovarian and prostate cancer...
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Posted: March 30th, 2010, 5:00am CDT
Some children with cancer could be given less intensive treatment than current practice to reduce their risk of damaging side-effects, according to a paper published in the Journal of Clinical Oncology today...
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Posted: March 30th, 2010, 5:00am CDT
Scientists are learning how our immune system senses and tracks down infection in the body by responding to chemical "scents" emitted by bacteria. Studying how immune cells manipulate their movement in response to external signals could shed light not only on how our immune system functions but also how cancer cells spread through the body and even how the brain wires itself...
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Posted: March 30th, 2010, 2:00am CDT
Investigators believe they have identified the founding member of a chemical family they hope will lead to a new class of cancer drugs, the first designed specifically against a childhood tumor, according to research led by St. Jude Children's Research Hospital scientists. The chemical is the first small-molecule inhibitor to target the MDMX protein...
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Posted: March 30th, 2010, 2:00am CDT
The first physician-scientist to combine radiation oncology with medical oncology - forever impacting the effect and importance of radiation oncology in treating people living with cancer - is among the notable awardees set to be honored by the American Society of Clinical Oncology (ASCO) at its 2010 Annual Meeting...
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Posted: March 30th, 2010, 2:00am CDT
Early detection through physical examination is one of the key factors in successfully treating prostate cancer. Now, health care providers will be able to gain applied training early in their medical education and careers with new simulation technology developed at the University of Virginia that will allow them to experience numerous scenarios that simulate prostate cancer...
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Posted: March 30th, 2010, 2:00am CDT
Tomato genes could be used as a future treatment in gene therapy, according to new research results from Lund University. Jure Piskur is a Professor at the Department of Biology, Lund University. Together with colleagues from Stockholm, Copenhagen and Lund, he has recently published research results on a tomato gene that it seems could be of value in future treatment of brain tumours...
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Posted: March 29th, 2010, 5:00am CDT
Undergoing surgical cancer treatment holds greater risk for people who also have diabetes than it does for people who just have cancer, according to a study being published this month in Diabetes Care...
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Posted: March 29th, 2010, 4:00am CDT
A two-drug combination destroys precancerous colon polyps with no effect on normal tissue, opening a new potential avenue for chemoprevention of colon cancer, a team of scientists at The University of Texas M. D. Anderson Cancer Center reports in the advance online edition of the journal Nature...
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Posted: March 29th, 2010, 4:00am CDT
People with diabetes who undergo cancer surgery are more likely to die in the month following their operations than those who have cancer but not diabetes, an analysis by Johns Hopkins researchers suggests...
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Posted: March 29th, 2010, 4:00am CDT
A small study of children with cancer enrolled in therapeutic clinical research trials shows that they don't fully understand what physicians and parents tell them about their participation, nor do they feel they are genuinely involved in the choice to take part. The study, led by Yoram Unguru, M.D...
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Posted: March 29th, 2010, 4:00am CDT
Antisoma plc (LSE: ASM; USOTC: ATSMY) announces that the planned interim analysis of data from the ATTRACT-1 phase III trial of ASA404 in previously untreated non-small cell lung cancer (NSCLC) has shown that continuation of the trial would be futile, as there is little or no prospect of demonstrating a survival benefit with ASA404 in this setting. The ATTRACT-1 trial will therefore be halted...
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Posted: March 29th, 2010, 3:00am CDT
Health Affairs: The Growing Financial Burden Of Health Care: National And State Trends, 2001-2006 - This paper examines the ratio of total out-of-pocket spending for health care and insurance to total family income, using data from the Medical Expenditure Panel Surveys for 2001-2006...
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Posted: March 29th, 2010, 2:00am CDT
Ocular melanoma, also known as melanoma of the eye or uveal melanoma is the most common type of eye cancer. Tumors arise from the melanocytes - pigment-producing cells - that reside within the uvea, giving color to the eye. Most melanomas grow in the skin, but some can develop in other parts of the body, including the eye...
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Posted: March 28th, 2010, 4:00am CDT
Tumors biopsied from women with invasive breast cancer are having their genomes sequenced in an attempt to develop a DNA profile that one day may identify ahead of time the patients who will most likely respond to chemotherapy with an aromatase inhibitor. Aromatase inhibitors are a class of chemotherapeutic agents that block the production of estrogen in postmenopausal women...
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Posted: March 28th, 2010, 3:00am CDT
While ASCO recognizes that there are strong feelings on both sides of this issue, we are very pleased that the newly passed Patient Protection and Affordable Care Act signed into law this week includes a number of things that will benefit cancer patients in the short term and the long term...
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Posted: March 28th, 2010, 3:00am CDT
UroToday.com - This is a large, nationwide, population-based investigation based on a widely used and validated food frequency questionnaire (FFQ). Nevertheless, possible limitations should be mentioned, in particular, the validity of information on intake of beverages 2 years before the study...
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Posted: March 28th, 2010, 2:00am CDT
In draft guidance, published, the National Institute for Health and Clinical Excellence (NICE) has asked Novartis Pharmaceuticals UK to provide more data on its product imatinib (Glivec) as an adjuvant treatment for people who have had a gastrointestinal stromal tumour removed and who are at risk of the cancer recurring...
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Posted: March 28th, 2010, 2:00am CDT
UroToday.com - In the journal Cancer, Dr. J. Kellogg Parsons and colleagues report on prostate cancer treatment for economically disadvantaged men in California. They found significant variations in prostate cancer treatment patterns by healthcare institutions providing care for disadvantaged as opposed to non-disadvantaged men. The database was a state funded program for lower income men...
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Posted: March 28th, 2010, 2:00am CDT
UroToday.com - The selection of appropriate candidates for partial nephrectomy, open, laparoscopic, or robotic, along with modern ablative therapies and active surveillance has been largely guided by the renal tumor sizes assessed via various imaging modalities...
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Posted: March 27th, 2010, 12:00pm CDT
In the online edition of the Journal of Clinical Oncology, Dr. Michael Zelefsky and colleagues from Memorial Sloan-Kettering report a retrospective study comparing radical prostatectomy (RP) and external beam radiotherapy (XRT) for localized prostate cancer (CaP). The clinical endpoints assessed were distant metastases (DM) and cancer-specific mortality...
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Posted: March 27th, 2010, 12:00pm CDT
Researchers from the University of Montreal, Maisonneuve-Rosemont Hospital and Laval University have discovered a channel to attack leukemia and other cancer cells, reports a new study published in the Journal of Biological Chemistry. This discovery of a previously hidden channel may alter the way doctors treat cancer patients...
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Posted: March 27th, 2010, 3:00am CDT
The University of Minnesota Medical School today announced the details of a $3.8 million grant by the National Institutes of Health's National Center on Minority Health and Health Disparities (NCMHD) for research focused on minority recruitment and retention in cancer clinical trials...
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Posted: March 27th, 2010, 3:00am CDT
Dr. Mamdooh Ghoneum discussed his findings on cancer research and treatment at the Egyptian Embassy in Washington, D.C. The event was sponsored by the Egyptian Cultural and Educational Bureau. Ghoneum, an Egyptian-born researcher and professor at Charles Drew University of Medicine and Science in Los Angeles, has been studying natural cures for cancer for more than two decades...
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Posted: March 27th, 2010, 2:00am CDT
Identification of two new proteins in the Fanconi anemia DNA repair pathway may help explain genetic instability in people with Fanconi anemia and how otherwise healthy people are susceptible to cancer from environmentally triggered DNA damage. A study in the March 26 Molecular Cell adds another layer of complexity to the multifaceted Fanconi anemia (FA) pathway...
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Posted: March 27th, 2010, 2:00am CDT
Preclinical Model of Primary Prostate Cancer A group led by Dr. Massimo Loda at the Dana Farber Cancer Institute, Boston, MA has generated a preclinical model of human prostate cancer that mimics the genetic and growth behavior of primary tumors. Their report can be found in the April 2010 issue of the American Journal of Pathology...
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Posted: March 27th, 2010, 2:00am CDT
Canadian researchers have discovered a previously hidden channel to attack leukemia and other cancer cells, according to a new study published in the Journal of Biological Chemistry. The findings from the Universite de Montreal, Maisonneuve-Rosemont Hospital and Universite Laval may change the way doctors treat cancer patients...
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Posted: March 26th, 2010, 8:00am CDT
Treatment with beta-blockers can help reduce the spread of cancer in patients with breast tumours, a researcher will tell the seventh European Breast Cancer Conference (EBCC7) in Barcelona today (Friday). In a controlled study, Dr...
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Posted: March 26th, 2010, 5:00am CDT
A new mechanism explaining how tumors escape the body's natural immune surveillance has recently been discovered at EPFL (Ecole Polytechnique Fédérale de Lausanne) in Switzerland. The study shows how tumors can create a tolerant microenviroment and avoid attack by the immune system by mimicking key features of lymph nodes...
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Posted: March 26th, 2010, 5:00am CDT
Research conducted and patented by Dr Mark Howard at the University of Kent's School of Biosciences has led to the development of a new technique that will deliver cancer treatments directly to certain tumours. One of the cancers this could have particular benefit in targeting is pancreatic cancer, which is currently very difficult to treat...
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Posted: March 26th, 2010, 4:00am CDT
A recent study found that sirolimus-based immunosuppression following liver transplantation in patients with non-resectable hepatocellular carcinoma (liver cancer) significantly increases survival rates for this patient population...
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Posted: March 26th, 2010, 4:00am CDT
Despite the fact that someone is diagnosed with bowel cancer every 15 minutes in the UK, many people are still unaware of the symptoms or of the simple steps they can take to help reduce their risk of developing the disease. That's why Bowel Cancer UK is once again promoting Bowel Cancer Awareness Month (BCAM) this April...
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Posted: March 26th, 2010, 4:00am CDT
US scientists have successfully completed a study where they showed targeted nanoparticles injected directly into a patient's bloodstream navigated into tumors, delivered double-stranded small interfering RNAs and turned off a gene that drives cancer growth...
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Posted: March 26th, 2010, 2:00am CDT
Researchers at the National Institute on Aging (NIA), part of the National Institutes of Health, have discovered a key to embryonic stem (ES) cell rejuvenation in a gene - Zscan4 - as reported in the March 24, 2010, online issue of Nature. This breakthrough finding could have major implications for aging research, stem cell biology, regenerative medicine and cancer biology...
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Posted: March 26th, 2010, 2:00am CDT
Arrhythmic hearts soon may beat in time again, with minimal surgical invasion, thanks to flexible electronics technology developed by a team of University of Illinois researchers, in collaboration with the University of Pennsylvania School of Medicine and Northwestern University. These biocompatible silicon devices could mark the beginning of a new wave of surgical electronics...
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Posted: March 26th, 2010, 2:00am CDT
Protein phosphorylation is a process by which proteins are flipped from one activation state to another. It is a crucial function for most living beings, since phosphorylation controls nearly every cellular process, including metabolism, gene transcription, cell-cycle progression, cytoskeletal rearrangement and cell movement...
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Posted: March 25th, 2010, 11:00pm CDT
The London Breast Clinic today announced that it is to be the first breast clinic in Europe to offer their patients BCtect®, a blood based test for early detection of breast cancer...
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Posted: March 25th, 2010, 9:00pm CDT
Varian Medical Systems (NYSE: VAR) invites investors and members of the financial community for a special presentation where members of senior management will unveil new technologies and approaches for radiotherapy and radiosurgery. The breakfast meeting will take place from 7:30 a.m. to 9:00 a.m. on Wednesday, April 14, 2010, in the IAC Building, 555 W. 18th St., New York...
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Posted: March 25th, 2010, 8:00pm CDT
One of the first hospitals in England to introduce intensity modulated radiotherapy (IMRT) treatments has now carried out its first procedure using fast and efficient RapidArc® image-guided IMRT from Varian Medical Systems (NYSE: VAR)...
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Posted: March 25th, 2010, 3:00am CDT
Dr. Matthias Selbach, biologist at the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, has been honored with the Analytica Research Prize 2010 in an award ceremony at the Analytica 2010 trade fair in Munich. Dr. Selbach received the prize, which is endowed with 25 000 euros, for his work on "the impact of microRNAs on protein production in cancer cells" on March 23, 2010...
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Posted: March 25th, 2010, 3:00am CDT
An experimental vaccine against an abnormal protein found in some tumors has the potential to delay the onset of inflammatory bowel disease (IBD) and in turn prevent progression to colon cancer, according to researchers at the University of Pittsburgh School of Medicine. Their findings are reported this week in Cancer Prevention Research, a journal of the American Association for Cancer Research...
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Posted: March 25th, 2010, 3:00am CDT
For Hempstead resident Lynette Love, mother of four and grandmother of five, surviving colorectal cancer took courage, diligence and faith. Now a 3-year survivor, Love is giving the love back to the community through her participation in the Sprint for Colorectal Oncology Prevention and Education (SCOPE) run. Love has joined The University of Texas M. D...
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Posted: March 25th, 2010, 3:00am CDT
The investigational compound that sparked excitement at ASCO last year for it's action against a difficult form of breast cancer, BSI-201, is now being evaluated for its efficacy against one of the most common and deadly forms of lung cancer - and the trial is now underway as it has just enrolled its first patient and in the process of enrolling others...
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Posted: March 25th, 2010, 3:00am CDT
The National Institute for Health and Clinical Excellence (NICE) has given its preliminary view that it is 'minded not to recommend' imatinib for the adjuvant (post surgery) treatment of adult patients with KIT (CD-117)-positive Gastrointestinal Stromal Tumours (GISTs), who are at significant risk of disease recurrence...
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Posted: March 24th, 2010, 7:00am CDT
As you stroll down restaurant row and catch the wonderful aroma of food - steaks, burgers, and grilled veggies - keep this in mind: You may be in an air pollution zone. Scientists in Minnesota are reporting that commercial cooking is a surprisingly large source of a range of air pollutants that could pose risks to human health and the environment...
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Posted: March 24th, 2010, 4:00am CDT
Biomedical researchers in Bergen are applying nanotechnology to mimic the body's natural processes, create new blood vessels to supply engineered tissue, and deepen our understanding of cancer. Effective combination Biomedical researchers around the globe are going all-out to induce cells to create new tissue. But all living tissues require a supply of blood to survive...
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Posted: March 24th, 2010, 3:00am CDT
When people think of cancer treatment, chemotherapy infusions, injections and pills often come to mind. These treatments result from extensive research and testing in drug development. But how does the process begin? One avenue is through discussion and the sharing of ideas in a forum provided by the National Cancer Institute's (NCI) Cancer Therapy Evaluation Program (CTEP)...
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Posted: March 24th, 2010, 3:00am CDT
The newest generation of "virtual biopsy" colonoscopy probes being tested at the Mayo Clinic campus in Florida demonstrate that it might soon be possible to use such a device to determine whether a colon polyp is benign and not remove it for biopsy...
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Posted: March 24th, 2010, 3:00am CDT
Postmenopausal women who regularly use aspirin and other analgesics (known as painkillers) have lower estrogen levels, which could contribute to a decreased risk of breast or ovarian cancer...
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Posted: March 24th, 2010, 2:00am CDT
A new, large-scale study of more than 10,000 adults found that more than one in every 200 asymptomatic people screened with CT colonography, or virtual colonoscopy, had clinically unsuspected malignant cancer and more than half of the cancers were located outside the colon. The findings were published in the April issue of the journal Radiology...
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Posted: March 23rd, 2010, 11:00am CDT
Chemotherapy is being received by fewer than half of Australian cancer patients for whom it would be recommended, according to new research released today by the Medical Oncology Group of Australia (MOGA)...
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Posted: March 23rd, 2010, 8:00am CDT
Merck Serono, a division of Merck KGaA, and its U.S. affiliate, EMD Serono, Inc. announced that they have temporarily suspended the clinical program for Stimuvax® (BLP25 liposome vaccine) in all recruiting studies worldwide as a result of a suspected unexpected serious adverse reaction (SUSAR). This decision was taken in alignment with the U.S...
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Posted: March 23rd, 2010, 6:00am CDT
A California Institute of Technology (Caltech)-led team of researchers and clinicians has published the first proof that a targeted nanoparticle - used as an experimental therapeutic and injected directly into a patient's bloodstream - can traffic into tumors, deliver double-stranded small interfering RNAs (siRNAs), and turn off an important cancer gene using a mechanism known ...
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Posted: March 23rd, 2010, 6:00am CDT
A new study has found that when African American and white cancer patients are treated at similar, specialized cancer care institutions, mortality rates are roughly equal. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the findings suggest that where patients receive care may partly explain observed racial disparities in cancer mortality...
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Posted: March 23rd, 2010, 6:00am CDT
CANCER Research UK launched a special Race for Life event in memory of Jade Goody , to take place in the reality star's adopted home county of Essex, on Sunday 6th June. A year on from her death, Jade's bridesmaids are calling on women to enter the commemorative event...
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Posted: March 23rd, 2010, 5:00am CDT
Before you dig in to your next stack of French toast or waffles, you might want to pour on pure maple syrup. That's because University of Rhode Island researcher Navindra Seeram, who specializes in medicinal plant research, has found more than 20 compounds in maple syrup from Canada that have been linked to human health, 13 of which are newly discovered in maple syrup...
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Posted: March 23rd, 2010, 4:00am CDT
"When a person receives a cancer diagnosis his or her life is completely transformed and all of the sudden they have so few choices," said Laura Morrell, social worker at Loyola University Health System's Cardinal Bernardin Cancer Center. Thirty-five women and one man who attend the Divine Savior Parish in Downers Grove, Ill., are helping to bring choice back into cancer patients' lives...
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Posted: March 23rd, 2010, 2:00am CDT
For an as yet unknown reason, cancer radiotherapy can increase the risk of cardiovascular disease later in life, a problem that is growing as more and more people survive their cancer diagnosis. New research from Karolinska Institutet now suggests that sustained inflammation induced by post-radiotherapy changes in the gene expression in the arteries could be the cause...
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Posted: March 23rd, 2010, 2:00am CDT
Molecular Insight Pharmaceuticals, Inc. (NASDAQ: MIPI) today announced the initiation of a Phase 1 clinical trial of Solazed™ (Ioflubenzamide I-131), the Company's targeted radiotherapeutic drug candidate for treatment of malignant metastatic melanoma...
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Posted: March 23rd, 2010, 2:00am CDT
Arrayit Corporation (OTCBB: ARYC), a leader in life sciences, healthcare and molecular diagnostics, announced that the company has appointed DOCRO, Inc. of Seymour, Connecticut, to assist in obtaining FDA approval for OvaDx...
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Posted: March 23rd, 2010, 2:00am CDT
Walnut consumption slows the growth of prostate cancer in mice and has beneficial effects on multiple genes related to the control of tumor growth and metabolism, UC Davis and the U.S. Department of Agriculture Western Regional Research Center in Albany, Calif. have found...
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Posted: March 22nd, 2010, 2:00pm CDT
Scientists from a leading European medical university suggest that the sustained inflammation in the arteries brought on by changes in gene expression as a result of cancer radiotherapy could be the reason why so many people who survive their cancer diagnosis go on to develop cardiovascular disease later in life...
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Posted: March 22nd, 2010, 3:00am CDT
UroToday.com - Fusion of the promoter/enhancer region of the androgen-responsive prostate specific serine protease 2-encoding gene, TMPRSS2 to the ETS variant 1 gene (ETV1) occurs uniquely in prostate cancer (CaP). Approximately 40-50% of CaP cases demonstrate a gene fusion. The most common fusion variant is a recombination between exon 1 of TMPRSS2 and exon 4 of ERG, designated T1/E4...
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Posted: March 22nd, 2010, 2:00am CDT
Researchers around the globe are working on turning microRNAs, over 5,000 of which already have been identified, into novel drugs for a wide range of applications, reports Genetic Engineering & Biotechnology News (GEN)...
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Posted: March 21st, 2010, 2:00am CDT
Novelos Therapeutics, Inc. (OTCBB: NVLT), a biopharmaceutical company focused on the development of therapeutics to treat cancer and hepatitis, announced that primary and secondary endpoints were not met in Novelos' pivotal Phase 3 trial in advanced non-small cell lung cancer (NSCLC) with its lead product, NOV-002, in combination with first-line chemotherapy...
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Posted: March 21st, 2010, 2:00am CDT
Provectus Pharmaceuticals, Inc. (OTC BB: PVCT), a development-stage oncology and dermatology biopharmaceutical company, announced that data from its Phase 2 study of PV-10 for metastatic melanoma has been accepted for presentation at the 2010 American Society of Clinical Oncology (ASCO) Scientific Program to be held on June 4 - 8, 2010 in Chicago, Illinois. Dr...
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Posted: March 21st, 2010, 2:00am CDT
At the United States & Canadian Academy of Pathology 2010 annual meeting (March 20-26, Washington DC, USA), Royal Philips Electronics (NYSE: PHG, AEX: PHI) will unveil a work-in-progress pathology slide scanner and associated image management system. These prototype systems will form the basis of the company's future integrated digital pathology solutions...
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Posted: March 20th, 2010, 4:00am CDT
Prometheus Laboratories Inc., a specialty pharmaceutical and diagnostic company, announced the execution of a research collaboration and license agreement with Bayer Schering Pharma AG, Germany, a worldwide leading specialty pharmaceutical company...
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Posted: March 20th, 2010, 4:00am CDT
MedSolutions, a leading provider of medical cost management services, announced the launch of its oncology management program, which uses evidence-based guidelines to ensure appropriate use of diagnostic imaging, radiation therapy and drugs for cancer patients...
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Posted: March 20th, 2010, 3:00am CDT
Moffitt Cancer Center and Proteacel LLC have announced that they have entered a licensing agreement under which Proteacel has acquired the exclusive rights to the PORE™ technology for delivery of genes into cells. Genes are the instructions that build cells. Defects in these genes cause disease, such as cancer...
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Posted: March 20th, 2010, 3:00am CDT
A $10.2 million commitment from the Robertson Foundation to create a state-of-the-art Translational Cell Therapy Center (TCTC) will advance Duke Medicine's pioneering cell therapy research and treatment programs for children and adults with cancer, cerebral palsy, stroke and brain injuries suffered at birth. In making the announcement, Victor J...
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Posted: March 20th, 2010, 2:00am CDT
GenWay Biotech, Inc., the US-based diagnostic company that recently launched the You Test YouTM Cancer Assessment is expanding this cancer testing program internationally. An agreement has been executed to offer the You Test You*trade; Cancer Assessment in Greece starting in April. Additional agreements are in progress for other European nations as well...
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Posted: March 19th, 2010, 7:00am CDT
Although Asian Americans have long been portrayed as a "model minority" with few major problems, data released online in the American Journal of Public Health (AJPH) reveal that distinct groups of Asian Americans, Native Hawaiians and Pacific Islanders (AA and NHPI) differ widely in death and disease rates, including from breast cancer and other conditions such as heart disease...
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Posted: March 19th, 2010, 7:00am CDT
WHO: Leaders of SNM Michael M. Graham, Ph.D., M.D., president, SNM Robert W. Atcher, Ph.D., M.B.A., past president, SNM; chair, SNM Medical Isotope Task Force Jeffrey P. Norenberg, Pharm.D., M.S...
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Posted: March 19th, 2010, 6:00am CDT
Cancer death rates for African-Americans far exceed non-Hispanic Caucasians in the United States, and only community-driven approaches to reducing health disparities will lessen the gap, says Edward Partridge, M.D., president-elect of the American Cancer Society (ACS) National Board of Directors and director of the University of Alabama at Birmingham (UAB) Comprehensive Cancer Center...
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Posted: March 19th, 2010, 5:00am CDT
Celsion Corporation ( CLSN) announced that an abstract about the Phase I/II trial of ThermoDox® in Recurrent Chest Wall Cancer (RCW) has been accepted for presentation at the American Society of Clinical Oncology (ASCO) 2010 Annual Meeting...
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Posted: March 19th, 2010, 4:00am CDT
UroToday - Our study of nephron sparing surgery in renal cell carcinoma (RCC) invading the segmental branches of the renal vein is consistent with the trend towards increased utilization of "partial nephrectomy" during surgical management of RCC...
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Posted: March 19th, 2010, 4:00am CDT
The Institute of Cancer Research (ICR) is to receive a milestone payment triggered by the first patient receiving a drug it helped develop in a Phase II clinical trial. The drug, an Hsp90 inhibitor known as AUY-922, is being tested in a range of cancers. It works by targeting and inactivating a crucial molecule called Hsp90, which cancer cells are dependant on for growth...
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Posted: March 19th, 2010, 4:00am CDT
A new preparation of an omega-3 polyunsaturated fatty acid found naturally in fish, offers hope for thousands of patients at risk of developing an inherited form of bowel cancer, a new study shows...
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Posted: March 19th, 2010, 3:00am CDT
Scientists report that breast cancer risk assessment models, which predict a woman's chance of developing breast cancer, do not perform better when they include common inherited genetic variants recently linked to the disease. Therefore, recommendations for breast cancer screening or treatments will remain unchanged for most women...
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Posted: March 19th, 2010, 2:00am CDT
Antisoma plc (LSE: ASM; USOTC: ATSMY) announces that it has started a randomised, controlled, multi-territory, phase IIb trial of AS1411 in patients with acute myeloid leukaemia (AML). Dr Ursula Ney, Chief Operating Officer of Antisoma, said: "AML is a devastating disease for which new treatment options are desperately needed...
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Posted: March 19th, 2010, 2:00am CDT
Researchers from The University of Texas M. D. Anderson Cancer Center report that in a small study of women with advanced or recurrent endometrial cancer, gemcitabine and cisplatin, when used in combination, produced a response rate in fifty percent of patients. Jubilee Brown, M.D., associate professor in M. D...
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Posted: March 19th, 2010, 2:00am CDT
According to a new study, who you see for prostate cancer heavily determines the treatment you will receive. The study, released by The Cancer Institute of New Jersey in New Brunswick and published in the Archives of Internal Medicine, claims that while most prostate cancer treatment options differ in many aspects, the majority of options are similar across the board...
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Posted: March 19th, 2010, 2:00am CDT
Human Genome Sciences, Inc. (Nasdaq: HGSI) announced the results of its randomized Phase 2 trial of mapatumumab (HGS-ETR1) in combination with the chemotherapy agents paclitaxel and carboplatin as first-line therapy in advanced non-small cell lung cancer (NSCLC). The results showed no difference in disease response or progression-free survival for the combination that included mapatumumab vs...
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Posted: March 19th, 2010, 2:00am CDT
Euthanasia, also known as assisted suicide, physician-assisted suicide (dying) , doctor-assisted dying (suicide) , and more loosely termed mercy killing, basically means to take a deliberate action with the express intention of ending a life to relieve intractable (persistent, unstoppable) suffering. Some interpret euthanasia as the practice of ending a life in a painless manner...
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Posted: March 18th, 2010, 7:00pm CDT
EDP Biotech, a Knoxville-based company today briefed Tennessee state legislators on its revolutionary ColoMarker™ colon cancer test which potentially could save 50,000 lives and more than $12 billion in healthcare costs annually in the U.S...
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Posted: March 18th, 2010, 8:00am CDT
The Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) review has been published in the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Radiation Oncology (ASTRO) to update recommendations for the safe irradiation of 16 organs. For each organ, the relationship between dose/volume and clinical outcome is reviewed...
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Posted: March 18th, 2010, 7:00am CDT
USA Today: "The cost of cancer treatment is 'skyrocketing' - both for individual patients and the nation, a new analysis shows. From 1990 to 2008, spending on cancer care soared to more than $90 billion from $27 billion...
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Posted: March 18th, 2010, 7:00am CDT
In recognition of Colorectal Cancer Awareness Month, The American College of Obstetricians and Gynecologists reminds ob-gyns and women that the best defense against colorectal cancer-the third leading cause of cancer death among women in the US-is getting screened...
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Posted: March 18th, 2010, 5:00am CDT
Increased understanding of the Skp2 gene and its relation to cellular senescence may lead to the development of novel agents that can suppress tumor development in common types of cancer, researchers from The University of Texas M. D. Anderson Cancer Center and Memorial Sloan-Kettering Cancer Center report in the journal Nature...
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Posted: March 18th, 2010, 4:00am CDT
Early findings suggest a radiation therapy that involves numerous highly-focused and potent radiation beams provides targeted tumor control in nearly all patients, reduces treatment-related illness, and may ultimately improve survival for patients with inoperable non-small cell lung cancer, according to a study in the March 17 issue of JAMA, a theme issue on cancer. Robert Timmerman, M.D...
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Posted: March 18th, 2010, 4:00am CDT
Palliative care services are available at most U.S. cancer centers, although the scope of services offered and the degree of integration between palliative care and oncology care varies widely among centers, according to a study in the March 17 issue of JAMA, a theme issue on cancer. David Hui, M.D., M.Sc., of the University of Texas M. D...
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Posted: March 18th, 2010, 4:00am CDT
Although there have been achievements in the battle against cancer, including a decrease in the rate of death and new diagnoses, cancer remains one of the leading causes of death in the U.S., with a need for continued improvement in the areas of prevention, detection and treatment, according to a commentary in the March 17 issue of JAMA, a theme issue on cancer. Susan M. Gapstur, Ph.D., M.P...
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Posted: March 18th, 2010, 4:00am CDT
Newspaper and magazine reports about cancer appear more likely to discuss aggressive treatment and survival than death, treatment failure or adverse events, and almost none mention end-of-life palliative or hospice care, according to a report in the March 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals...
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Posted: March 18th, 2010, 4:00am CDT
New chemotherapy agents appear associated with improvements in survival time for patients with metastastic colorectal cancer, but at substantial cost. David H. Howard, Ph.D...
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Posted: March 18th, 2010, 4:00am CDT
PCI Biotech reported that it has completed the treatment of the third dose group in the phase I/II study of its proprietary photosensitiser Amphinex® used in combination with the cytotoxic agent bleomycin in cancer patients...
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Posted: March 18th, 2010, 4:00am CDT
A study from The University of Texas M. D. Anderson Cancer Center reports that cancer centers in the United States provide patients and their families with palliative care, though the depth, range and integration of programs and services widely vary...
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Posted: March 18th, 2010, 4:00am CDT
Two US cancer nurses have researched the evidence behind a commonly applied rule that cancer patients should not apply skin creams or lotions for four hours before having radiotherapy treatment and found there is little evidence to support this belief and that practice varies widely. Trish Bieck and Shannon Phillips from the James P...
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Posted: March 18th, 2010, 3:00am CDT
The National Foundation for Cancer Research has announced that renowned scientist Peter K. Vogt, Ph.D., Professor in the Department of Molecular and Experimental Medicine at The Scripps Research Institute, La Jolla, California, is the recipient of the 5th Annual Szent-Gyorgyi Prize for Progress in Cancer Research. Dr...
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Posted: March 18th, 2010, 3:00am CDT
Even though older patients with colon cancer are less likely to receive chemotherapy following surgery because of concerns of adverse events, new research indicates that when they do receive this treatment, it is less toxic and of shorter duration than therapy younger patients receive, and older patients experience fewer adverse events, according to a study in the March 17 issu...
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Posted: March 18th, 2010, 2:00am CDT
Doctors have a clearer picture than ever before of how much radiation reaches sensitive tissues during routine X-rays and similar imaging, thanks to sophisticated models of the human body being developed at the University of Florida...
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Posted: March 18th, 2010, 2:00am CDT
UCSF researchers have discovered that a key cellular defect that disturbs the production of proteins in human cells can lead to cancer susceptibility. The scientists also found that a new generation of inhibitory drugs offers promise in correcting this defect...
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Posted: March 18th, 2010, 2:00am CDT
"To manage the future costs and quality of care for patients with skin cancer, a revised health strategy is needed," write Simone van der Geer, M.D., of Erasmus University Medical Center, Rotterdam, and colleagues in a special article...
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Posted: March 18th, 2010, 2:00am CDT
African Americans and Hispanic patients appear less likely than white patients to have access to high-quality surgical care for brain tumors, according to a report in the March issue of Archives of Surgery, one of the JAMA/Archives journals. The article is one of several in the issue focusing on cancer, and is being published in conjunction with a JAMA theme issue on cancer...
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Posted: March 18th, 2010, 2:00am CDT
Research published ahead of print in the journal Gut reports that a purified form of an omega 3 cuts the number and size of precancerous bowel growths (polyps) in people whose genetic make-up predisposes them to bowel cancer. This particular omega 3 is eicosapentaenoic acid or EPA...
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Posted: March 18th, 2010, 1:00am CDT
Early detection of melanoma appears more common among younger patients, those living in areas with high concentrations of dermatologists and those whose cancer is detected by dermatologists. Frédérique Durbec, M.D., of Hôpital Robert Debré, France, and colleagues studied new cases of cutaneous melanoma in five regions of northeastern France in 2004...
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Posted: March 18th, 2010, 12:00am CDT
Treating melanoma in older adults is estimated to cost approximately $249 million annually. Anne M. Seidler, M.D., M.B.A., Emory University School of Medicine, Atlanta, and colleagues used national databases to assess health care resource consumption by a total of 1,858 patients age 65 and older with melanoma during fiscal years 1991 to 1996...
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Posted: March 17th, 2010, 11:00pm CDT
Survivors of one melanoma appear approximately nine times as likely as the general population to develop a second melanoma. Porcia T. Bradford, M.D., and colleagues at the National Cancer Institute, Bethesda, Md., used nine cancer registries to identify 89,515 patients who survived at least two months after an initial melanoma diagnosis between 1973 and 2006. Of these, 10,857 (12...
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Posted: March 17th, 2010, 10:00pm CDT
Both new diagnoses and a history of non-melanoma skin cancer appear to have become increasingly common, and the disease affects more individuals than all other cancers combined, according to two reports in the March issue of Archives of Dermatology, one of the JAMA/Archives journals...
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Posted: March 17th, 2010, 3:00pm CDT
US researchers who analysed over a decade's worth of statistics on non-melanoma skin cancers in the US (the country's most common form of cancer) found they have been rising steadily every year, and concluded that their findings reveal the "most complete evaluation to date of the underrecognized epidemic of skin cancer in the United States"...
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Posted: March 17th, 2010, 8:00am CDT
Women who take the birth control pill are more likely to live longer than women who have never taken the pill, according to a study published Friday in the British medical journal BMJ, the AP/Boston Globe reports. Researchers in the United Kingdom followed more than 46,000 women who took the pill and then compared the mortality rate of those women with women who did not take birth control pills...
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Posted: March 17th, 2010, 8:00am CDT
Cells have two different protection programs to safeguard them from getting out of control under stress and from dividing without stopping and developing cancer. Until now, researchers assumed that these protective systems were prompted separately from each other...
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Posted: March 17th, 2010, 7:00am CDT
UroToday.com - Adult bone marrow-derived mesenchymal stem cells (MSC) have been shown to inhibit tumor growth in various studies. Although MSC express MHC class I molecules, they lack expression of co-stimulatory molecules and suppress T-cell response, which gives them the utility to overcome a wide range of immunologic barriers...
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Posted: March 17th, 2010, 6:00am CDT
UroToday.com - Despite significant improvements in surgical technique, preoperative preparation and perioperative care since the inception of radical cystectomy (RC), the complication rate associated with this operation remains high. Patients requiring RC are elderly with considerable associated comorbidities due to the strong association of cigarette smoking and urothelial bladder carcinoma...
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Posted: March 17th, 2010, 6:00am CDT
Cryotherapy, an interventional radiology treatment to freeze cancer tumors, may become the treatment of the future for cancer that has metastasized in soft tissues (such as ovarian cancer) and in bone tumors...
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Posted: March 17th, 2010, 6:00am CDT
False alarms from lung cancer screening can cause substantial negative psychological and social consequences. A Danish research project where healthy heavy smokers were screened with CT-scans has shown that a suspicion of having lung cancer results in anxiety, a sense of dejection, sleeping problems and has a negative impact on behaviour...
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Posted: March 17th, 2010, 5:00am CDT
An interventional radiology treatment the use of intra-arterial yttrium-90 microspheres for liver cancer (also known as hepatocellular carcinoma) shows promise in prolonging life for many patients with this devastating condition, according to researchers at the Society of Interventional Radiology's 35th Annual Scientific Meeting in Tampa, Fla...
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Posted: March 17th, 2010, 5:00am CDT
Improving on traditional screening tests for potential anti-cancer drugs, scientists at Dana-Farber Cancer Institute have developed a laboratory technique that more closely simulates the real-world conditions in which tumor cells mingle with the body's normal cells...
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Posted: March 17th, 2010, 4:00am CDT
A radiation therapy that uses multiple radiation beams to target tumors precisely has been shown to eliminate the primary tumor and ultimately may improve survival rates for lung-cancer patients unable to undergo surgery, according to UT Southwestern Medical Center physicians who led a national clinical trial of the treatment...
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Posted: March 17th, 2010, 4:00am CDT
Case management appears to be associated with more appropriate follow-up and shorter time to diagnostic resolution among low-income women who receive an abnormal result on a mammogram, according to a report in the March 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. Rebecca Lobb, Sc.D., M.P.H., of the Centre for Research on Inner City Health, St...
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Posted: March 17th, 2010, 4:00am CDT
A vaccine designed to prevent cervical cancer also may protect females from post-surgical recurrence of the disease, according to researchers at the University of Alabama at Birmingham (UAB)...
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Posted: March 17th, 2010, 3:00am CDT
Like a magician who says, "Pick a card, any card," Stanford University computer scientist Debashis Sahoo, PhD, seemed to be offering some kind of trick when he asked researchers at the Stanford Institute for Stem Cell Biology and Regenerative Medicine to pick any two genes already known to be involved in stem cell development...
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Posted: March 17th, 2010, 3:00am CDT
BioSante Pharmaceuticals, Inc. (NASDAQ: BPAX) announced BioSante's receipt of Orphan Drug designation from the FDA's Office of Orphan Products Development for GVAX Pancreas Vaccine in the treatment of pancreatic cancer...
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Posted: March 17th, 2010, 2:00am CDT
Despite cancer survival rates increasing dramatically for children and older adults in the last 20 years, there has been minimal improvement in the survival rates in the Adolescent and Young Adult (AYA) population, an age range defined as 15 - 29 years by the presenters...
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Posted: March 16th, 2010, 8:00am CDT
Many visits by dying cancer patients to the emergency department can be avoided with effective palliative care, states an article in the Canadian Medical Association Journal (CMAJ). In Ontario, about 40% of cancer patients visit the emergency department in the last 2 weeks of life...
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Posted: March 16th, 2010, 8:00am CDT
Treating non-osteoporotic compression fractures in patients with multiple myeloma, a blood cancer, shows that the use of vertebroplasty - a minimally invasive treatment performed by interventional radiologists using imaging guidance that stabilizes collapsed vertebrae with the injection of medical-grade bone cement into the spine - results in a reduction of pain, medication usa...
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Posted: March 16th, 2010, 7:00am CDT
Mammograms, pap smears and early detection tests for prostate cancer, colorectal cancer and other malignancies are critical for catching cancer before it becomes deadly...
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Posted: March 16th, 2010, 7:00am CDT
UroToday.com - The availability of novel and promising targeted therapies for the treatment of patients with metastatic renal cell carcinoma (RCC), such as bevacizumab plus interferon and sunitinib, has meant important increases in options for patients and physicians treating this deadly disease. It has also meant that patients can take medications, non-curatively, for long periods of time...
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Posted: March 16th, 2010, 7:00am CDT
PARASITOLOGY: Cancer drug beneficial in models of infectious disease Drugs known as receptor tyrosine kinase inhibitors (RTKIs) are routinely used to treat several forms of cancer, but whether they could be used to effectively treat infectious diseases has not been determined...
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Posted: March 16th, 2010, 6:00am CDT
New data from an NIH-sponsored, multi-site study of hundreds of women with newly diagnosed breast cancer shows that Positron Emission Mammography (PEM) may reduce unnecessary breast biopsies...
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Posted: March 16th, 2010, 6:00am CDT
MDRNA, Inc. (NASDAQ: MRNA), a leading RNAi-based drug discovery and development company, announced enhanced efficacy for tumor reduction when two UsiRNA were combined within a single formulation. The UsiRNAs targeted two proteins survivin, a protein involved in cell division and inhibition of apoptosis, and PLK1 (Polo-like Kinase 1), a protein involved in cell mitosis and tumor progression...
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Posted: March 16th, 2010, 6:00am CDT
The muscle-building abilities of hormones known as insulin-like growth factors (IGFs) are legendary. Just do an online search and you'll find not only scientific papers discussing the effects of IGFs on the cells that give rise to muscle tissue, but also scores of ads touting the purported benefits of IGF supplements for bodybuilding...
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Posted: March 16th, 2010, 6:00am CDT
The link between obesity and disease has been well documented. There's evidence now that obesity and cancer have a strong link, as they've shown in the United States at least 90,000 cancer deaths a year can be attributed to obesity. University of Alberta researcher Richard Lamb is on his way to understanding the correlation and it's a good example of how the scientific process works...
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Posted: March 16th, 2010, 5:00am CDT
Physiomics, the Oxford-based systems biology company, and Sareum Holdings plc are pleased to announce that they have signed an agreement in which Physiomics provides in silico simulations to support Sareum's cancer drug joint research program with The Institute of Cancer Research (ICR) and Cancer Research Technology Limited (CRT)...
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Posted: March 16th, 2010, 5:00am CDT
More than 1,200 operating room nurses attended this morning's breakfast forum "Together We Can Save Lives Through Early Detection" sponsored by Medline Industries, Inc., expecting to hear Olympic gold medalist Peggy Fleming talk about her skating career and battle with breast cancer. Fleming did not disappoint the early morning crowd...
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Posted: March 16th, 2010, 4:00am CDT
African-American, Hispanic, and economically disadvantaged patients with brain tumors are significantly less likely to be referred to high-volume hospitals that specialize in neurosurgery than other patients of similar age, the same gender, and with similar comorbidities, according to new research by Johns Hopkins doctors...
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Posted: March 16th, 2010, 4:00am CDT
The film "Avatar" isn't the only 3-D blockbuster making a splash this winter. A team of Houston scientists this week unveiled a new technique for growing 3-D cell cultures, a technological leap from the flat petri dish that could save millions of dollars in drug-testing costs. The research is reported in Nature Nanotechnology...
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Posted: March 16th, 2010, 4:00am CDT
Cancer Research UK-funded scientists have discovered that the gene defects that cause some bowel cancers could become the targets for new personalised treatments. Their research is published in Cancer Cell yesterday (Monday). Around five per cent of bowel cancers are caused by inherited mutations in one of two genes, either MLH1 or MSH2...
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Posted: March 16th, 2010, 3:00am CDT
Drugs increasingly used to treat cancer could have a major impact on a wide range of infectious diseases, according to new research. Anti-angiogenic drugs are used to try and prevent cancers from stimulating the growth of the blood vessels they need to survive and grow...
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Posted: March 16th, 2010, 3:00am CDT
A powerful new tool available at the University of Virginia Health System offers treatment to patients with some of the most challenging cancers of the head and neck. For more than 20 years, the University of Virginia Health System has provided patients treatment that uses radiation instead of a scalpel to eliminate deep-seated tumors without damaging surrounding healthy tissue...
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Posted: March 16th, 2010, 2:00am CDT
The European Medicines Agency has been formally notified by Mylan S.A.S. of its decision to withdraw its application for a centralised marketing authorisation for the medicinal product Docetaxel Mylan (docetaxel), 10mg/ml powder and solvent for solution for infusion...
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Posted: March 15th, 2010, 6:00am CDT
Bio-Path Holdings, Inc. (OTCBB: BPTH), a publicly traded biotechnology company with drug development operations in Houston, Texas, announced that the U.S. Food and Drug Administration (FDA) has allowed an IND (Investigational New Drug) for the Company's lead cancer drug candidate liposomal Grb-2 to proceed into clinical trials...
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Posted: March 15th, 2010, 6:00am CDT
Using risk stratification to assist in treatment selection was just one of the focal points at a recent presentation of the NCCN Clinical Practice Guidelines for Oncology (NCCN Guidelines™) for Acute Myeloid Leukemia (AML) at the NCCN 15th Annual Conference. B...
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Posted: March 15th, 2010, 6:00am CDT
Despite the advances and groundbreaking research being performed in the area of cancer treatment, sometimes cancer cannot be cured. In this situation, patients and their families are faced with complex emotions and a variety of end of life issues and decisions...
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Posted: March 15th, 2010, 6:00am CDT
The escalating costs of cancer care combined with variations in concordance with evidence-based practice guidelines is putting the United States on a collision course for an impending collapse of its current health care system according to roundtable panelists at the NCCN 15th Annual Conference...
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Posted: March 15th, 2010, 4:00am CDT
Scientists headed by ICREA researcher Marco Milan, at the Institute for Research in Biomedicine (IRB Barcelona), reveal a surprising new function of Notch protein that contrasts with the one known to date. Found in the cell membrane, this protein activates a signalling pathway that regulates the expression of genes that make the cell divide, grow, migrate, specialise or die...
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Posted: March 15th, 2010, 4:00am CDT
The Ontario Institute for Cancer Research (OICR) announced a significant investment toward the development of two new promising cancer therapies. The recipients of the awards are: Sunnybrook Health Sciences Centre, for Kullervo Hynynen's low-cost focused ultrasound system...
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Posted: March 15th, 2010, 3:00am CDT
In a lecture he delivered in 1906, the German physician Paul Ehrlich coined the term Zauberkugel, or "magic bullet," as shorthand for a highly targeted medical treatment. Magic bullets, also called silver bullets, because of the folkloric belief that only silver bullets can kill supernatural creatures, remain the goal of drug development efforts today...
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Posted: March 15th, 2010, 2:00am CDT
Helicobacter pylori, a bacterium found in about 50% of humans worldwide, can cause stomach ulcers and, in extreme cases, gastric cancer. In an article for F1000 Medicine Reports, Seiji Shiota and Yoshio Yamaoka discuss the possible eradication of H. pylori infections Infection by the H. pylori bacterium can approach 100% in developing countries...
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Posted: March 14th, 2010, 1:00am CST
Genentech, Inc., a wholly owned member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), announced today the topline results of a Phase III trial led by the U.S...
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Posted: March 14th, 2010, 1:00am CST
Pfizer Inc. announced today the discontinuation of A4021018 (also known as ADVIGO 1018), a Phase 3 trial examining the effects of investigational compound figitumumab (CP-751,871) in combination with erlotinib as a second/third-line treatment in patients with previously treated advanced non-adenocarcinoma non-small cell lung cancer (NSCLC)...
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Posted: March 14th, 2010, 1:00am CST
Pfizer Inc. announced today that two Phase 3 studies of Sutent® (sunitinib malate) in advanced breast cancer did not meet their primary endpoints...
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Posted: March 14th, 2010, 1:00am CST
The Human Papillomavirus (HPV) is the causative agent responsible for most cases of cervical cancer, but is also associated with several other types of cancer...
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Posted: March 14th, 2010, 1:00am CST
BioSante Pharmaceuticals, Inc. (NASDAQ: BPAX) announced positive results of a human clinical study that show that its GVAX Leukemia vaccine may be able to reduce or eliminate the last remaining cancer cells in some chronic myeloid leukemia (CML) patients taking the drug Gleevec (imatinib mesylate)...
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Posted: March 13th, 2010, 3:00am CST
Chemotherapy, followed by the surgical removal of the affected tissue is the treatment usually adapted to bone tumors. An implant which can fill the areas of subtraction, while releasing chemotherapeutical agents locally, in a controlled manner, during the treatment period, is the aim of a research led by the Research Centre in Ceramic Material and Composites (CICECO/UA)...
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Posted: March 13th, 2010, 3:00am CST
Sexual problems are frequent after operations for carcinoma of the rectum. Christian Schmidt et al. describe the consequences for quality of life in the current issue of Deutsches Arzteblatt International (Dtsch Arztebl Int 2010; 107[8]: 123-30). In Germany, each year more than 70,000 people develop colorectal carcinoma...
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Posted: March 13th, 2010, 2:00am CST
A research team led by the University of Colorado at Boulder has discovered a previously unknown cellular "switch" that may provide researchers with a new means of triggering programmed cell death, findings with implications for treating cancer...
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Posted: March 13th, 2010, 2:00am CST
Monash Institute of Pharmaceutical Science (MIPS) researchers, in collaboration with the biotechnology company Starpharma Holdings Ltd (ASX:SPL) have developed a new method to deliver medications that may benefit thousands of patients with particular types of cancer, HIV and lymphatic conditions world-wide...
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Posted: March 13th, 2010, 2:00am CST
Cancer cells in rapidly growing brain tumors must adjust to periods of low energy or die. When energy levels are high, tumor cells grow and proliferate. When levels are low, the cells grow less and migrate more. Researchers at the Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J...
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Posted: March 13th, 2010, 2:00am CST
Conventional biological wisdom holds that living cells interact with their environment through an elaborate network of chemical signals. As a result many therapies for the treatment of cancer and other diseases in which cell behavior goes awry focus on drugs that block or disrupt harmful chemical signals...
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Posted: March 12th, 2010, 10:00am CST
The majority of new cancer tests coming to market are proprietary assays with the test services being provided by certified labs opened by the IVD companies that developed the tests. All the major reference labs in North America and Europe are also offering a slew of in-house developed diagnostic tests...
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Posted: March 12th, 2010, 4:00am CST
Cancer patients in Kent will gain access to advanced radiotherapy treatments with the decision by the Kent Oncology Centre to acquire two fully-equipped treatment machines from Varian Medical Systems (NYSE: VAR)...
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Posted: March 12th, 2010, 4:00am CST
Clinicians at the Rinecker Proton Therapy Center (RPTC) in Munich have treated their 100th patient using advanced proton therapy systems supplied by Varian Medical Systems (NYSE: VAR). The landmark treatment comes just three months after a second treatment gantry was commissioned at the center, which offers advanced pencil-beam proton scanning to cancer patients...
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Posted: March 12th, 2010, 3:00am CST
Mount Sinai School of Medicine is leading a study of patients newly-diagnosed with prostate cancer to determine if providing them with multimedia materials can help them make more informed treatment decisions. Michael Diefenbach, Ph.D...
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Posted: March 12th, 2010, 3:00am CST
The European Medicines Agency has been formally notified by Ark Therapeutics Ltd of its decision to withdraw its application for a centralised marketing authorisation for the advanced therapy medicinal product Cerepro (sitimagene ceradenovec). Cerepro received an orphan designation on 6 February 2002 and was intended for the treatment of patients with high-grade operable glioma...
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Posted: March 12th, 2010, 2:00am CST
Mayo Clinic is forming a new permanent professorship to augment cancer research that will focus on finding new treatments and preventive measures to reduce the incidence of cancer. This professorship is made possible by a $2 million gift from The Vasek and Anna Maria Polak Charitable Foundation, and the recipient, Keith Stewart, M.B., Ch.B., has been approved by the Mayo Clinic Board of Trustees...
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Posted: March 12th, 2010, 2:00am CST
BioAlliance Pharma SA (Paris:BIO), a company dedicated to the treatment and supportive care of cancer and AIDS patients, announced positive preliminary results from the first Phase I trial of fentanyl Lauriad®...
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Posted: March 12th, 2010, 1:00am CST
The Cancer Prevention and Research Institute of Texas (CPRIT) today awarded over $6.8 million to fund twelve new cancer prevention programs through local clinics, health districts, community-based organizations, and academic institutions across the state of Texas. This is the very first round of prevention grants awarded in CPRIT's 10-year, $3 billion mission...
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Posted: March 11th, 2010, 6:00pm CST
NICE has published a draft clinical guideline on the use of ablative therapies for the treatment of Barrett's oesophagus. Ablative therapies destroy the abnormal cells within the oesophagus caused by the condition, without removing an entire section of oesophagus...
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Posted: March 11th, 2010, 8:00am CST
If you can imagine identical twin sisters at rest, their breath drawing them subtly together and apart, who somehow latch onto ropes that pull them to opposite sides of the bed - you can imagine what happens to a chromosome in the dividing cell...
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Posted: March 11th, 2010, 6:00am CST
About four out of every 10 cells in the brain are so-called oligodendrocytes. These cells produce the all-important myelin that coats nerve tracts, ensuring fast, energy-efficient transmission of nerve impulses...
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Posted: March 11th, 2010, 6:00am CST
While subjective patient-reported outcomes, such as scores from health-status questionnaires, have become an integral part of clinical trials, there is also a need to identify what specific outcomes are the most important ones to target in a given disease context...
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Posted: March 11th, 2010, 5:00am CST
Aided by ultrasound guidance, treating tumors with extreme heat or moderate heat may provide a possible therapeutic option, according to early research presented at the second AACR Dead Sea International Conference on Advances in Cancer Research: From the Laboratory to the Clinic, held March 7-10, 2010...
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Posted: March 11th, 2010, 4:00am CST
New Maryland legislation to protect youth from melanoma, the deadliest form of skin cancer, is based on significant scientific evidence that indoor tanning before the age of 30 is undeniably linked to increased risk of developing the disease. Senator James N. Robey and Delegate William A...
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Posted: March 11th, 2010, 4:00am CST
Physicians may be able to safely lower the platelet dosage in transfusions for cancer and bone-marrow transplant patients without risking increased bleeding, according to new research involving UT Southwestern Medical Center and 28 other medical institutions...
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Posted: March 11th, 2010, 3:00am CST
For patients like 10-year-old Sabrina Jo Spence, new research led by St. Jude Children's Research Hospital investigators meant fewer injections to combat the drop in white blood cells following her recent chemotherapy. "Cool," Sabrina told Sheri Spunt, M.D., an associate member of the St. Jude Department of Oncology, after hearing the news and breaking into what Sabrina called her "happy dance...
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Posted: March 11th, 2010, 3:00am CST
Digestive CARE™, a medical group of more than 50 gastroenterologists in Broward and Palm Beach County, announced that it is receiving hundreds of online votes in its "Bottom Line Song Title Contest" to bring awareness to National Colorectal Cancer Awareness Month (March 2010). Digestive CARE™ is urging people to go to the Web site http://www.DigestiveCareOnline...
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Posted: March 11th, 2010, 2:00am CST
The Howard Hughes Medical Institute (HHMI) has selected five exceptional individuals to receive the 2010 Gilliam Fellowships for Advanced Study. These students will join a dynamic group of 30 Gilliam fellows, who share a passion for science and a commitment to increasing diversity in the sciences. "It's been very gratifying to see the impact of the Gilliam fellows program," says Peter J...
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Posted: March 11th, 2010, 2:00am CST
The Vilcek Foundation is pleased to announce the granting of the 2010 Vilcek Prize for Biomedical Science to Dr. Alexander Varshavsky, the Howard & Gwen Laurie Smits Professor of Cell Biology at California Institute of Technology, for elucidating the process and biological significance of regulated protein degradation in living cells...
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Posted: March 11th, 2010, 2:00am CST
After making a diagnosis of cancer, clinicians have a number of treatment options. Most of these involve coordinating multiple attacks on the tumor using an arsenal of cancer-killing therapies. Chemotherapy, where toxic drugs are used to specifically kill cancer cells, is a very powerful weapon in this arsenal...
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Posted: March 11th, 2010, 1:00am CST
Chronix Biomedical today announced publication of a study that supports the utility of its serum DNA blood tests for the early and accurate detection of breast cancer. The Chronix tests detect the circulating DNA that is released into the blood stream by damaged and dying cells...
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Posted: March 10th, 2010, 7:00pm CST
It's long been known that obesity is linked to increased risk of developing colon cancer, but now researchers at the Mayo Clinic campus in Minnesota have found that obesity is associated with worse outcomes in patients who have already been diagnosed and treated for the cancer...
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Posted: March 10th, 2010, 11:00am CST
Scientists in the US who undertook a large study to investigate what biological mechanisms might be behind the already established link between colorectal cancer and consumption of red and processed meat, confirmed that such a link exists and suggested the main players are three compounds: heme iron, nitrate/nitrite, and heterocyclic amines...
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Posted: March 10th, 2010, 10:00am CST
Alison Walker, MD, has been selected to receive the ASH-AMFDP Award, and will begin her research in acute myeloid leukemia in July of this year...
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Posted: March 10th, 2010, 7:00am CST
A Princeton University-led research team has discovered that protein competition over an important enzyme provides a mechanism to integrate different signals that direct early embryonic development. The work suggests that these signals are combined long before they interact with the organism's DNA, as was previously believed, and also may inform new therapeutic strategies to fight cancer...
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Posted: March 10th, 2010, 6:00am CST
Individuals with a certain type of genetic susceptibility to lung cancer face a greatly increased risk for the deadly disease with even a small exposure to cigarette smoke, a study team that includes researchers from the University of Cincinnati (UC) has concluded...
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Posted: March 10th, 2010, 4:00am CST
Cellectar, Inc., a privately held radiopharmaceutical company that designs and develops products to detect, treat and monitor human cancers, announced that enrollment for its Phase I dosimetry trial for its lead drug candidate, (131)I-CLR1404 has been completed. Results of this trial will be used to set the starting dose in a follow-on Phase I dose escalation study planned for later this year...
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Posted: March 10th, 2010, 4:00am CST
The humble papaya is gaining credibility in Western medicine for anticancer powers that folk cultures have recognized for generations. University of Florida researcher Nam Dang, M.D., Ph.D., and colleagues in Japan have documented papaya's dramatic anticancer effect against a broad range of lab-grown tumors, including cancers of the cervix, breast, liver, lung and pancreas...
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Posted: March 10th, 2010, 3:00am CST
What began as research into how diabetics could possibly preserve their eyesight has led to findings that could prolong the vision of children afflicted with retinoblastoma...
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Posted: March 10th, 2010, 3:00am CST
The interaction of a ligand (Neurotrophine-3) and its dependence receptor (TrkC) constitutes a novel mechanism for tumor control in pediatric cancers such as neuroblastoma, and may also be important to the inhibition of other cancers such as breast cancer...
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Posted: March 10th, 2010, 3:00am CST
Changes in patients' self-rated quality of life after treatment for esophago-gastric cancer can predict the chances for long-term survival. This is the result researchers at the Swedish medical university Karolinska Institutet made, in a new study published in the Journal of Clinical Oncology. The patient's self-rated quality of life, provide indications of whether he or she will survive...
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Posted: March 10th, 2010, 3:00am CST
For the first time, scientists have succeeded in growing empty particles derived from a plant virus and have made them carry useful chemicals. The external surface of these nano containers could be decorated with molecules that guide them to where they are needed in the body, before the chemical load is discharged to exert its effect on diseased cells...
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Posted: March 10th, 2010, 2:00am CST
mtm laboratories, a privately held diagnostics company announced the launch of CINtec® PLUS, the company's next generation cervical cancer screening product with unmatched accuracy for the screening and management for cervical cancer...
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Posted: March 10th, 2010, 1:00am CST
Rexahn Pharmaceuticals, Inc. (NYSE Amex: RNN), a clinical stage pharmaceutical company commercializing potential best in class oncology and CNS therapeutics, today announced that the Japanese Patent Office has issued a patent for its novel anti-cancer compound, Archexin®...
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Posted: March 10th, 2010, 12:00am CST
Argos Therapeutics announced the presentation of positive data from a Phase 2 trial that evaluated the safety, clinical response and immune response of AGS-003 treatment in newly diagnosed patients with metastatic renal cell carcinoma (mRCC). The data were discussed March 7 in a poster presentation at the ASCO Genitourinary Cancers Symposium...
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Posted: March 9th, 2010, 7:00pm CST
Millennium: The Takeda Oncology Company today announced the presentation of safety, pharmacokinetic and efficacy data from the Phase I portion of a Phase I/II clinical trial evaluating TAK-700 in patients with metastatic castration resistant prostate cancer (mCRPC)...
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Posted: March 9th, 2010, 6:00pm CST
ImmunoGen, Inc. (Nasdaq: IMGN), a biotechnology company that develops targeted anticancer products using its antibody expertise and Targeted Antibody Payload (TAP) technology, announced that the US Food and Drug Administration (FDA) has granted orphan drug designation to its IMGN901 compound when used for the treatment of Merkel cell carcinoma (MCC)...
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Posted: March 9th, 2010, 7:00am CST
A new method of growing arteries could lead to a "biological bypass" - or a non-invasive way to treat coronary artery disease, Yale School of Medicine researchers report with their colleagues in the April issue of Journal of Clinical Investigation. Coronary arteries can become blocked with plaque, leading to a decrease in the supply of blood and oxygen to the heart...
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Posted: March 9th, 2010, 7:00am CST
Pharmaceutical companies could substantially reduce the expense of costly treatments for cancer and other diseases produced from mammalian or bacterial cells by growing these human therapeutic proteins in algae - rapidly growing aquatic plant cells that have recently gained attention for their ability to produce biofuels...
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Posted: March 9th, 2010, 6:00am CST
Immune cells ensnare dangerous cells that are on the run with a bungee-like nanotube, according to research published in the Proceedings of the National Academy of Sciences. The study, by researchers from Imperial College London, shows that natural killer (NK) cells use this bungee to destroy cells that could otherwise escape them...
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Posted: March 9th, 2010, 6:00am CST
New breakthrough treatments for the most common cancers could soon come from cutting-edge research into some of the world's rarest tumors...
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Posted: March 9th, 2010, 5:00am CST
Warning sign for potential anticancer approach One treatment being investigated as an adjuvant for anticancer immunotherapies is the use of molecules that trigger the proteins TLR7 and TLR8. For example, the TLR7 stimulant imiquimod is used for the treatment of skin cancer and metastatic melanoma...
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Posted: March 9th, 2010, 4:00am CST
Another weapon in the arsenal against cancer: Nanoparticles that identify, target and kill specific cancer cells while leaving healthy cells alone. Led by Carl Batt, the Liberty Hyde Bailey Professor of Food Science, the researchers synthesized nanoparticles shaped something like a dumbbell made of gold sandwiched between two pieces of iron oxide...
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Posted: March 9th, 2010, 3:00am CST
One in three early stage breast cancer patients who received genomic testing when deciding about treatment options felt they did not fully understand their discussions with physicians about their test results and their risk of the disease recurring, a new study has found...
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Posted: March 9th, 2010, 2:00am CST
Varian Medical Systems (NYSE: VAR) announced that it has appointed John R. Adler, Jr., M.D., as Vice President and Chief of New Clinical Applications for the company. Dr. Adler, a renowned neurosurgeon, professor of Neurosurgery and Radiation Oncology at Stanford University, and past CEO, chairman and founder of Accuray, Inc...
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Posted: March 8th, 2010, 7:00am CST
Life Technologies Corporation (NASDAQ:LIFE) announced that it is collaborating with the Translational Genomics Research Institute (TGen) and US Oncology to sequence the genomes of 14 patients afflicted with triple negative breast cancer whose tumors have progressed despite multiple other therapies...
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Posted: March 8th, 2010, 6:00am CST
According to a new study, men employed in occupations with potential exposure to high levels of sunlight have a reduced risk of kidney cancer compared with men who were less likely to be exposed to sunlight at work. The study did not find an association between occupational sunlight exposure and kidney cancer risk in women...
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Posted: March 8th, 2010, 6:00am CST
New Century Infusion Solutions, Inc. (NCIS), the first Oncology Benefit Management (OBM) company, is pleased to announce the publication of a white paper by the Lewin Group: "Medicare Cancer Care Coordination Using The Integrated Single Specialty Provider (ISSP) Model." The report estimates that over a 10-year horizon, a payer could realize oncology savings of "$16...
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Posted: March 8th, 2010, 5:00am CST
MIT chemical engineers have built a sensor array that, for the first time, can detect single molecules of hydrogen peroxide emanating from a single living cell...
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Posted: March 8th, 2010, 4:00am CST
Health Affairs this month is devoted to the topic of childhood obesity, with the first study of the group - National, State, And Local Disparities In Childhood Obesity - pointing out that "new data from the 2007 National Survey of Children's Health show that the percentage of children ages 10-17 who are overweight ...
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Posted: March 7th, 2010, 3:00am CST
The frequency of post-operative complications following surgery for liver cancer is associated with a hospital having a low volume of liver surgery. Investigators at The Cancer Institute of New Jersey (CINJ) are presenting that finding at the 63rd Annual Society of Surgical Oncology Symposium taking place this week in St. Louis...
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Posted: March 7th, 2010, 2:00am CST
Predictive Biosciences announced that the Company will be presenting its novel Multi-Analyte Diagnostic Readout (MADR™) approach to the development of a non-invasive, urinary biomarker based assay for the detection of bladder cancer during the 2010 Genitourinary Cancers Symposium (GU Symposium), being held March 5-7 in San Francisco...
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Posted: March 7th, 2010, 2:00am CST
Amber J. Belcher, a doctoral student in psychology at the University of Delaware, has won the Ruth L. Kirschstein National Research Service Award from the National Institutes of Health (NIH). The fellowship will support Belcher's research on how couples cope with breast cancer. Breast cancer is second only to skin cancer as the most common cancer among women in the United States...
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Posted: March 6th, 2010, 3:00am CST
Cholangiocarcinoma (CCA), a bile duct cancer, is one of the major cancers in Northeast Thailand. This cancer is difficult to diagnose and has high metastatic and mortality rates. Overexpression of Met, a hepatocyte growth factor (HGF) receptor, has frequently been found in CCA and is correlated with progression of this type of cancer...
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Posted: March 6th, 2010, 3:00am CST
Liver transplantation specialists recently convened to address U.S. guidelines for allocation of organs for patients with hepatocellular carcinoma (HCC, liver cancer). Representatives from more than 130 U.S. transplant centers were invited to the conference and participants included 180 leaders in liver transplantation (LT) from the 50 most active centers...
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Posted: March 5th, 2010, 7:00am CST
Men who undergo prostate-cancer screening should discuss with a doctor the uncertainties, risks and benefits of the test before it is performed, says Edward Partridge, M.D., president-elect of the American Cancer Society (ACS) National Board of Directors and director of the University of Alabama at Birmingham (UAB) Comprehensive Cancer Center...
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Posted: March 5th, 2010, 7:00am CST
American Cancer Society issued its new Guideline for the Early Detection of Prostate Cancer. The American Urological Association (AUA), which represents more than 16,000 urologists and urologic health professionals worldwide, issued the following statement in response to the new ACS document. The statement is attributable to AUA President Anton J. Bueschen, MD...
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Posted: March 5th, 2010, 5:00am CST
Covidien (NYSE: COV), a leading global provider of healthcare products, today announced that Mallinckrodt Inc., a Covidien company, has launched its Oral Transmucosal Fentanyl Citrate (CII) to distributors serving retail pharmacies across the country. The U.S...
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Posted: March 5th, 2010, 5:00am CST
The second American Association for Cancer Research Dead Sea International Conference on Advances in Cancer Research: From the Laboratory to the Clinic provides attendees with an overview of the most advanced cancer research in a variety of fields, including the tumor microenvironment, microRNAs, signal transduction and novel therapeutic development...
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Posted: March 5th, 2010, 4:00am CST
Responding to continued debate over PSA screening, and today's American Cancer Society statement, the Prostate Cancer Foundation (PCF) reiterated its position that PSA screening remains a valuable tool, in combination with other tools, for identifying potential prostate disease, including cancer...
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Posted: March 5th, 2010, 4:00am CST
At a recent community education program, Stanford experts on women's cancer disagreed with controversial new federal guidelines on breast cancer screening. The new guidelines, released in November by the U.S. Preventive Services Task Force, would delay a woman's first mammogram by 10 years, reduce future screenings from annual to every other year, and end them after age 74...
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Posted: March 5th, 2010, 4:00am CST
Health Dialog, a leading provider of healthcare analytics and decision support, today announced that its decision support tools for prostate cancer screening have been made available for the month of March as a public service offering...
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Posted: March 5th, 2010, 4:00am CST
During the 39th Annual Meeting of the American Association for Dental Research, convening at the Walter E. Washington Convention Center in Washington, DC, lead researcher M. Tong, The Ohio State University, will present a poster of a study titled "Epithelial-to-Endothelial Transition: An Epithelial Phenotypic Modulation Facilitating Oral-Squamous-Cell Carcinoma Progression...
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Posted: March 5th, 2010, 3:00am CST
Time taken to detect brain tumours could soon be significantly reduced thanks to an ongoing pioneering project led by the University of Liverpool with the Nuclear Physics Group and Technology departments at the Science and Technology Facilities Council (STFC) at Daresbury Laboratory...
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Posted: March 5th, 2010, 2:00am CST
In a new study from The University of Texas M. D. Anderson Cancer Center, researchers found that cystoscopy, the standard for screening for recurrence of early-stage bladder cancer, is a cost-effective method of detecting tumors...
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Posted: March 5th, 2010, 2:00am CST
Research published in the March edition of the Journal of Thoracic Oncology (JTO) explored the importance of a patient's outlook as it relates to health behavior and health status. Researchers focused on lung cancer patients and discovered that those who exhibited an optimistic disposition experienced more favorable outcomes than those with a pessimistic disposition...
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Posted: March 5th, 2010, 2:00am CST
Abbott (NYSE: ABT) announced that it has entered into an agreement with GlaxoSmithKline (GSK) to develop a molecular diagnostic test intended for use as an aid in selecting patients who may benefit from a skin cancer treatment in development by GSK...
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Posted: March 4th, 2010, 10:00pm CST
The National Institute for Health and Clinical Excellence (NICE) has today (4 March) issued final draft guidance recommending the drug rituximab(MabThera) as a treatment for certain patients with relapsed or refractory chronic lymphocytic leukaemia...
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Posted: March 4th, 2010, 10:00am CST
New studies on the treatment of genitourinary cancers were released today in advance of the third annual Genitourinary Cancers Symposium, being held March 5-7, 2010, at the San Francisco Marriott...
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Posted: March 4th, 2010, 9:00am CST
Next generation technology is set to revolutionize medical imaging by enabling earlier detection of brain tumors with one scan, improving the diagnosis and therapy of cancer, and increasing patient throughput in hospitals, according to news of a pioneering UK project...
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Posted: March 4th, 2010, 2:00am CST
A 2001 federal law mandates care for Medicare-eligible patients enrolled in clinical trials; however, only 25 state laws cover clinical-trial related medical costs for non-Medicare patients, and these offer less protection than the federal law. A lawyer explains these findings in a special article published online March 2 in the Journal of the National Cancer Institute...
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Posted: March 3rd, 2010, 5:00pm CST
Cancer Research UK re-release 'Girls Just Wanna Have Fun' to launch Race for Life 2010 Hundreds of women from across the UK have joined over 20 celebrities to record a unique charity single in aid of Cancer Research UK's Race for Life...
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Posted: March 3rd, 2010, 10:00am CST
Women who take some types of bone-building drugs used to prevent and treat osteoporosis may be at lower risk of breast cancer, according to a study by U.S. researchers published today in the British Journal of Cancer...
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Posted: March 3rd, 2010, 9:00am CST
Freezing a cancer kills it in its place, and also appears to generate an immune response that helps stop the cancer's spread, leading to improved survival rates over surgery, according to a new study in mice from researchers at the University of Michigan Comprehensive Cancer Center...
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Posted: March 3rd, 2010, 8:00am CST
A combination of two targeted therapies already shown to be effective in breast cancer packs an effective one-two punch against a subset of gastric cancers that have a specific genetic mutation, a study at UCLA's Jonsson Comprehensive Cancer Center has found...
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Posted: March 3rd, 2010, 8:00am CST
The Society of Interventional Radiology (SIR) will present the latest research on treatments for individuals with liver, breast, soft tissue, colon, prostate, lung and pancreatic cancers; painful spinal fractures; peripheral arterial disease (PAD); uterine fibroids; and more at its 35th Annual Scientific Meeting March 13 -18 at the Tampa Convention Center...
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Posted: March 3rd, 2010, 7:00am CST
In only its second year as an Affiliate Member of Radiation Therapy Oncology Group (RTOG), US Oncology, Inc. announced that its wholly-owned subsidiary US Oncology Research, LLC placed second amongst all affiliate members in patients accrued to RTOG clinical trials...
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Posted: March 3rd, 2010, 6:00am CST
The culmination of a two-year effort to review available studies and establish new guidelines for the safe treatment of cancer with radiation therapy was published in the International Journal of Radiation Oncology, Biology and Physics...
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Posted: March 3rd, 2010, 5:00am CST
The benefits of using insulin to treat diabetes far outweigh the risks, but a review just published online by IJCP, the International Journal of Clinical Practice, suggests that commonly used diabetes therapies may differ from each other when it comes to their influence on cancer risk...
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Posted: March 3rd, 2010, 4:00am CST
In a bold, eye-opening editorial in the March 2010 issue of the Journal of Ultrasound in Medicine, Harvard Professor, Beryl Benacerraf, MD, urges the medical community to use ultrasound instead of Computed Tomography (CT) as the first-line imaging test for better diagnosis capability in the evaluation of acute female pelvic and lower abdominal conditions...
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Posted: March 3rd, 2010, 4:00am CST
ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) announced that its investigational pan-BCR-ABL inhibitor, AP24534, has been granted orphan drug designation by both the U. S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA). In the U.S...
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Posted: March 3rd, 2010, 3:00am CST
Recent reports of President Obama's CT colonography, or virtual colonoscopy, as a screening test for colorectal cancer and coverage by the Associated Press of an NIH State-of-the-Science conference heralding stool blood tests as an inexpensive alternative to colonoscopy may leave many consumers wondering which colorectal cancer test is best for them...
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Posted: March 3rd, 2010, 3:00am CST
ChemGenex Pharmaceuticals Limited (ASX:CXS) announced that the U.S. Food and Drug Administration (FDA) has rescheduled the previously postponed Oncologic Drugs Advisory Committee (ODAC) meeting to 22 March 2010...
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Posted: March 3rd, 2010, 2:00am CST
Boston University School of Medicine's (BUSM) researchers have found that sociodemographic characteristics are related to a patients' willingness to participate in cancer screenings. They found this was more important than both attitudinal barriers and medical facilitors. This study appears in the March issue of the Journal of the National Medical Association...
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Posted: March 3rd, 2010, 2:00am CST
The next treatment for cancer might come from fish says a new research report published in the March 2010 print edition of the FASEB Journal (http://www.fasebj.org). In the report, scientists show that the omega-3 fatty acid, "docosahexaenoic acid" or "DHA," and its derivatives in the body kill neuroblastoma cancer cells...
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Posted: March 3rd, 2010, 2:00am CST
A study published on bmj.com today reports that the longer women wait for radiotherapy after breast cancer surgery, the more chance there is of local recurrence. Starting radiotherapy as soon as possible will minimize this risk according to the authors. The reasonable generally accepted interval between cancer surgery and radiotherapy is four to six weeks...
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Posted: March 2nd, 2010, 2:00pm CST
Acculis Limited today announced the regulatory clearance of its revolutionary new device for destroying unwanted tissues, such as liver tumours. The clearance under the European CE Mark system allows the company to begin deliveries for treating patients throughout Europe and elsewhere where the CE Mark system is recognised. The device is a single high power high frequency 2...
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Posted: March 2nd, 2010, 12:00pm CST
Synta Pharmaceuticals Corp. (NASDAQ: SNTA), a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today announced that Dr. Geoffrey I...
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Posted: March 2nd, 2010, 7:00am CST
Overexpression of the ARD1A gene (arrest-defective protein 1225) in mice reduced the number and size of both primary tumors and metastases, researchers report in a new study published online March 1 in the Journal of the National Cancer Institute. ARD1A blocks the expression of VEGFA (vascular endothelial growth factor A), an important mediator of blood vessel growth in tumors...
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Posted: March 2nd, 2010, 6:00am CST
CytoCore Inc...
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Posted: March 2nd, 2010, 6:00am CST
According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), older men with high levels of the hormone IGF-I (insulin-like growth factor 1) are at increased risk of cancer death, independent of age, lifestyle and cancer history...
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Posted: March 2nd, 2010, 5:00am CST
Cancer Research UK scientists have developed a system to identify faulty or missing genes that could prevent specific chemotherapy regimes from working. This opens the doors for targeted breast cancer treatment, according to research published in the Lancet Oncology...
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Posted: March 2nd, 2010, 4:00am CST
Office-based, surgeon-performed, ultrasound-guided, fine needle aspiration (FNA) of head and neck lesions yields a statistically significant higher diagnostic rate compared to the standard palpation technique, indicates new research in the March 2010 issue of Otolaryngology - Head and Neck Surgery. FNA is a diagnostic procedure used to investigate superficial lumps or masses...
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Posted: March 2nd, 2010, 4:00am CST
The challenges facing young women with breast cancer, and the promise of high-tech cancer care in rural settings, are the subjects of innovative new grants addressing real-life issues in cancer care, awarded by the ASCO Cancer Foundation®, with funding from Susan G. Komen for the Cure®. The $2...
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Posted: March 2nd, 2010, 2:00am CST
When treating cancer, it is an advantage to know the rate of growth of the cancer tumour. The standard method currently used to determine tumour growth, however, is erroneous. This is the conclusion of scientists at the University of Gothenburg, Sweden, who have developed a new model...
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Posted: March 2nd, 2010, 2:00am CST
A survey of parents who had a child die of cancer found that one in eight considered hastening their child's death, a deliberation influenced by the amount of pain the child experienced during the last month of life, report Dana-Farber Cancer Institute researchers in the March issue of Archives of Pediatrics & Adolescent Medicine...
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Posted: March 2nd, 2010, 2:00am CST
Researchers have designed a urine test that can simultaneously measure the extent of a potential carcinogenic process and a marker of garlic consumption in humans. In a small pilot study, the test suggested that the more garlic people consumed, the lower the levels of the potential carcinogenic process were...
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Posted: March 1st, 2010, 5:00pm CST
Parents and clinicians caring for children with brain tumors may experience significant challenges near the end of life due to the neurologic deterioration that often occurs in these patients. Shayna Zelcer, M.D., F.R.C.P.C...
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Posted: March 1st, 2010, 5:00pm CST
Children with the most common childhood cancer did not experience improved outcomes from participating in a clinical trial between 1997 and 2005. Carl Koschmann, M.D...
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Posted: March 1st, 2010, 5:00pm CST
In a study of 141 parents whose children have died of cancer, more than 10 percent reported that they considered hastening their child's death, especially if the child was in pain, according to a report in the March issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals...
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Posted: March 1st, 2010, 6:00am CST
Many cancer patients in Europe are being denied access to adequate pain relief because of over-zealous regulations restricting the availability and accessibility of opioid-based drugs such as morphine...
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Posted: March 1st, 2010, 4:00am CST
Researchers at Rhode Island Hospital have discovered how cells communicate with each other during times of cellular injury. The findings shed new light on how the body repairs itself when organs become diseased, through small particles known as microvesicles, and offers hope for tissue regeneration...
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Posted: March 1st, 2010, 2:00am CST
While biomarkers are needed to complement ultrasound in the early detection of hepatocellular carcinoma (HCC; liver cancer), neither des-gamma-carboxy prothrombin (DCP) nor the most widely used biomarker, alpha fetoprotein (AFP), is optimal, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute...
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Posted: March 1st, 2010, 2:00am CST
Huixin He, associate professor of nanoscale chemistry at Rutgers University, Newark, and Tamara Minko, professor at the Rutgers Ernest Mario School of Pharmacy, have developed a nanotechnology approach that could potentially eliminate the problems of side effects and drug resistance in the treatment of cancer...
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Posted: March 1st, 2010, 2:00am CST
Medicare regulations require that when patients receive some types of highly specialized cancer treatments, their radiation oncologist must be on site. But The New York Times reports that federal officials are investigating a Florida cancer clinic that billed Medicare for such treatments while the doctors were absent, sometimes on overseas trips...