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Cholesterol-Lowering Drugs From Website Advertising Risky For Purchasers
Posted: February 5th, 2012, 2:00am CST
A new study published in the journal Pharmacoepidemiology & Drug Safety reveals that internet sites selling prescription statins directly to consumers are widespread, and that most websites advertising statins for sale to the general public contain very poor levels of information relevant to safe use of the medicine and side effects... -
Statins Work As Well On Females As Males
Posted: January 31st, 2012, 2:00pm CST
Statins given to female patients are as effective in preventing the occurrence of cardiovascular events as they are for men, researchers from Boston and New York reported in the Journal of the American College of Cardiology. Cardiovascular events include stroke, heart attack, and angina. William J. Kostis, Ph.D., M.D... -
Study Of Genetic Regulation Of Metabolomic Biomarkers - Paths To Cardiovascular Diseases And Type 2 Diabetes
Posted: January 30th, 2012, 3:00am CST
In a study into the genetic variance of human metabolism, researchers have identified thirty one regions of the genome that were associated with levels of circulating metabolites, i.e., small molecules that take part in various chemical reactions of human body... -
Identification Of Entry Point For Hepatitis C Infection
Posted: January 26th, 2012, 2:00am CST
A molecule embedded in the membrane of human liver cells that aids in cholesterol absorption also allows the entry of hepatitis C virus, the first step in hepatitis C infection, according to research at the University of Illinois at Chicago College of Medicine... -
Statins May Work Against Certain Breast Cancers
Posted: January 23rd, 2012, 4:00am CST
Statins are commonly prescribed to lower cholesterol, but a recent study suggest certain types of breast cancer may respond to treatment with statins... -
A Biomarker Test For Atherosclerosis To Seek Out The Silent Killer
Posted: January 14th, 2012, 2:00am CST
Furring of the arteries, atherosclerosis, is a leading cause of death across the world. Atherosclerosis leads to peripheral arterial disease, coronary heart disease, stroke and heart attacks. However, atherosclerosis is a sneaky killer - most people do not realize they have it until they have cardiovascular disease (CV)... -
Novel Target In Artery Plaque Discovered As Potential Therapeutic Intervention
Posted: January 10th, 2012, 5:00am CST
A new study by NYU Langone Medical Center researchers identified a new culprit that leads to atherosclerosis, the accumulation of fat and cholesterol that hardens into plaque and narrows arteries. The research, published online by Nature Immunology on January 8, 2012, explains why cholesterol-laden, coronary artery disease-causing cells called macrophages, accumulate in artery plaques... -
Benefits Of Statin Therapy May Extend Beyond Lowering Lipids
Posted: January 6th, 2012, 2:00am CST
People with high cholesterol are at risk of heart attack and stroke because atherosclerotic plaques within their arteries can rupture triggering the formation of a blood clot called an occlusive thrombus that cuts off the blood supply to their heart or brain. For years, scientists have studied the cause of this abnormal clotting... -
As Part Of A Heart-Healthy Diet, Eating Lean Beef Daily Can Help Lower Cholesterol
Posted: December 28th, 2011, 2:00am CST
A new study published in the January 2012 edition of American Journal of Clinical Nutrition shows that beef can play a role in a cholesterol-lowering diet, despite commonly held beliefs. The study found that diets including lean beef every day are as effective in lowering total and LDL "bad" cholesterol as the "gold standard" of heart-healthy diets (DASH, Dietary Approaches to Stop Hypertension)... -
Cholesterol-Lowering Drugs May Reduce Mortality For Influenza Patients
Posted: December 17th, 2011, 4:00am CST
Statins, traditionally known as cholesterol-lowering drugs, may reduce mortality among patients hospitalized with influenza, according to a new study released online by The Journal of Infectious Diseases... -
Cholesterol-Lowering Medication Accelerates Depletion Of Plaque In Arteries
Posted: December 14th, 2011, 4:00am CST
In a new study, NYU Langone Medical Center researchers have discovered how cholesterol-lowering drugs called statins promote the breakdown of plaque in the arteries. The study was published online by the journal PLoS One on December 6, 2011... -
Agent Responsible For Protection Against Early Stages Of Atherosclerosis Identified
Posted: December 14th, 2011, 3:00am CST
Researchers from Boston University School of Medicine (BUSM) have identified for the first time the A2b adenosine receptor (A2bAR) as a possible new therapeutic target against atherosclerosis resulting from a diet high in fat and cholesterol. The findings, which appear on-line in Circulation, may have significant public health implications... -
Low-Density Lipoprotein Treatment Breakthrough
Posted: December 12th, 2011, 11:00am CST
A novel breakthrough advance in fighting low-density lipoprotein (LDL) or "bad" cholesterol in the body has been announced by investigators from the University of Leicester and University of California Los Angeles (UCLA). The universities have filed two patents in order to develop targeted medications designed to lower levels of LDL... -
New Advance Announced In Reducing 'bad' Cholesterol
Posted: December 10th, 2011, 2:00am CST
Scientists from the University of Leicester and the University of California Los Angeles (UCLA) have announced a major advance towards developing drugs to tackle dangerous, or 'bad', cholesterol in the body. They have filed two patents for developing targeted drugs that would act as a catalyst for lowering levels of 'bad' cholesterol... -
New Advance Announced In Reducing 'Bad' Cholesterol
Posted: December 10th, 2011, 2:00am CST
Scientists from the University of Leicester and the University of California Los Angeles (UCLA) have announced a major advance towards developing drugs to tackle dangerous, or 'bad', cholesterol in the body. They have filed two patents for developing targeted drugs that would act as a catalyst for lowering levels of 'bad' cholesterol... -
Potential Breast Cancer Prevention Agent Found To Lower Levels Of 'Good' Cholesterol Over Time
Posted: December 10th, 2011, 2:00am CST
Exemestane steadily lowered levels of "good" cholesterol in women taking the agent as part of a breast cancer prevention study, say researchers at Georgetown Lombardi Comprehensive Cancer Center. Exemestane, an aromatase inhibitor used to treat estrogen receptor-positive breast cancer, is being tested to prevent breast cancer in women at an increased risk of developing the disease... -
New Advance Announced In Reducing 'bad' Cholesterol
Posted: December 9th, 2011, 4:00am CST
Scientists from the University of Leicester and the University of California Los Angeles (UCLA) have announced a major advance towards developing drugs to tackle dangerous, or 'bad', cholesterol in the body. They have filed two patents for developing targeted drugs that would act as a catalyst for lowering levels of 'bad' cholesterol... -
Preventing Atherosclerosis
Posted: December 9th, 2011, 3:00am CST
By changing the behavior of certain cells within human blood vessels, Cornell University researchers have discovered important clues as to the underlying causes of atherosclerosis - a discovery researchers hope can lead to more targeted drug therapies for the prevention of the disease... -
Gene Mutation Allows You To Have Your Cream And Eat It, Too
Posted: December 7th, 2011, 3:00am CST
People who carry a malfunctioning copy of a particular gene are especially good at clearing fat from their systems. The report in the December Cell Metabolism, a Cell Press publication, shows how the mutant gene influences metabolism in this way... -
End Of The Road For Pfizer's Lipitor
Posted: December 1st, 2011, 9:00pm CST
The FDA approved today a generic version of Pfizer's Lipitor, one of the world's best selling drugs. Known pharmaceutically as atorvastatin calcium tablets, Lipitor is used to reduce cholesterol. The generic version will be manufactured by Ohm Laboratories in New Brunswick, N.J. Cholesterol itself is not a major problem and is, in fact, an essential nutrient for the body... -
Cholesterol-Lowering Lipitor: FDA Okays First Generic Version
Posted: December 1st, 2011, 5:00am CST
The US Food and Drug Administration (FDA) announced on Wednesday that it has approved the first generic version of the world's top-selling medicine, the cholesterol-lowering drug Lipitor (atorvastatin), currently marketed by Pfizer Inc... -
Cholesterol Levels And Heart Disease Biomarkers In Diabetics Improved By Vitamin D-Fortified Yoghurt
Posted: November 27th, 2011, 2:00am CST
People with diabetes are known to have an increased risk of heart disease. New research published in BioMed Central's open access journal BMC Medicine shows that regular consumption of a vitamin D-fortified yoghurt drink improves cholesterol levels and biomarkers of endothelial dysfunction, a precursor of heart disease, in diabetics... -
Vascular Lipid Accumulation Seen In Young Transparent Zebrafish
Posted: November 23rd, 2011, 2:00am CST
A study using genetically modified zebrafish to visualize early events involved in development of human atherosclerosis describes an efficient model - one that the researchers say offers many applications for testing the potential effectiveness of new antioxidant and dietary therapies... -
Possible New Target For Atherosclerosis Treatment - Hormone That Controls Iron Levels
Posted: November 18th, 2011, 3:00am CST
Researchers at Emory University School of Medicine have identified hepcidin, a hormone that regulates iron levels in the body, as a potential target for treating atherosclerosis. Suppressing hepcidin is a way to reduce the iron levels inside the white blood cells found in arterial plaques... -
New Research May Provide Clues Into The Molecular Links Between Psoriasis And Heart Disease
Posted: November 18th, 2011, 3:00am CST
Collaborative research from Perelman School of Medicine at the University of Pennsylvania has shown that psoriasis patients have an increased risk of heart attack, stroke and cardiovascular death, especially if the psoriasis is moderate to severe. Now, Penn researchers have discovered the potential underlying mechanism by which the inflammatory skin disease impacts cardiovascular health... -
Niacin Does Not Reduce Heart Attack, Stroke Risk In Stable, Cardiovascular Patients Whose Cholesterol Is Well-Controlled To Treatment Guidelines
Posted: November 18th, 2011, 2:00am CST
At the American Heart Association meeting, UB professor of medicine William E. Boden, MD, discussed the AIM-HIGH clinical trial, which found that niacin provides no incremental benefit to patients with atherosclerotic heart disease, whose levels of LDL cholesterol and non-HDL (which contributes to plaque in the arteries) were very well-controlled... -
Green Tea May Lower "Bad" Cholesterol, New Analysis
Posted: November 17th, 2011, 4:00am CST
A new analysis of published studies finds that consuming green tea, either as a beverage or in capsule form, is linked to significant but modest reductions in total and LDL or "bad" cholesterol, but the researchers found no link with HDL or "good" cholesterol and triglycerides. Dr Olivia J... -
Long-Term Antiepileptic Drug Therapy And Vascular Risk
Posted: November 16th, 2011, 4:00am CST
New research reveals that patients with epilepsy who were treated for extended periods with older generation antiepileptic drugs (AEDs) may be at increased risk for developing atherosclerosis, a common disorder known as hardening of the arteries... -
Crestor Same As Lipitor In Stabilizing Plaque In Arteries
Posted: November 15th, 2011, 6:00pm CST
Crestor is not significantly better at stabilizing plaque and reducing cholesterol, compared to Lipitor, a Pfizer drug that Ranbaxy Laboratories will launch in much cheaper generic versions in two weeks' time... -
Niacin Does Not Reduce Heart Attack Risk When Bad Cholesterol Is Well Controlled
Posted: November 15th, 2011, 11:00am CST
Adding high doses of extended-release niacin to reduce improve cholesterol levels will not reduce heart attack or stroke risk for patients with stable, chronic heart disease whose LDL cholesterol is well controlled, researchers reported in NEJM (New England Journal of Medicine). They also presented their findings at the American Heart Association's Scientific Sessions 2011... -
New Drug Evacetrapib Raises 'Good' Cholesterol And Lowers 'Bad' Cholesterol Levels
Posted: November 15th, 2011, 7:00am CST
A study presented at the American Heart Association Scientific sessions shows that the use of the medication evacetrapib alone or in conjunction with statin drugs was linked to a considerable increase in high-density lipoprotein cholesterol (HDL-C) and decreases in low-density lipoprotein cholesterol (LDL-C) amongst patients with sub-optimal LDL-C or HDL-C. The study is published in the Nov... -
British Heart Foundation Response To New Cholesterol Drug - Evacetrapib
Posted: November 15th, 2011, 7:00am CST
High LDL, or bad cholesterol levels increase the risk of developing cardiovascular diseases, especially in those with high LDL levels and low levels of HDL (good cholesterol)... -
Cholesterol Lowered By Injection In Preliminary Human Trial
Posted: November 15th, 2011, 5:00am CST
Patients unable to control their cholesterol levels with medications may someday be able to lower their "bad" cholesterol with a shot, according to research presented at the American Heart Association's Scientific Sessions 2011... -
Protection Against Atherosclerosis From Dendritic Cell Subtype
Posted: November 13th, 2011, 2:00am CST
Atherosclerosis, commonly referred to as "hardening of the arteries," is a major risk factor for heart attack and stroke. The cause of atherosclerosis is not well understood but, for some time, chronic inflammatory immune responses have been implicated in driving disease pathology... -
Check Children's Cholesterol Levels, New Guidelines, USA
Posted: November 12th, 2011, 12:00pm CST
Children should be checked for blood cholesterol levels between 9 and 11, and then again between 17 and 21 years, the National Institutes of Health (NIH) has announced in new guidelines for doctors. The NIH says the guidelines have been endorsed by the American Academy of Pediatrics. In other words, two cholesterol checks before the age of 21... -
Promising New Therapy For Treating Cardiovascular Disease Being Tested On Non-Human Primates
Posted: November 1st, 2011, 2:00am CDT
A new therapy being studied in non-human primates by researchers at Wake Forest Baptist Medical Center and colleagues is demonstrating promise as a potential tool for combating cardiovascular disease by increasing good cholesterol and lowering triglycerides in the blood... -
Atherosclerosis Reduced By Watermelon In Animal Model
Posted: October 31st, 2011, 2:00am CDT
In a recent study by University of Kentucky researchers, watermelon was shown to reduce atherosclerosis in animals. The animal model used for the study involved mice with diet-induced high cholesterol. A control group was given water to drink, while the experimental group was given watermelon juice... -
Soy Protein Improves Lipid Profile In Healthy Individuals
Posted: October 23rd, 2011, 2:00am CDT
A new study published online in the European Journal of Clinical Nutrition shows that soy protein compared to dairy milk protein supplementation improves the lipid profile in healthy individuals. This study investigated the effect of soy and milk protein supplementation on lipids compared with carbohydrate among healthy adults... -
Novel Therapeutic Target Identified To Decrease Triglycerides And Increase "Good" Cholesterol
Posted: October 21st, 2011, 3:00am CDT
Researchers at NYU Langone Medical Center announce findings published in the October 20 issue of Nature that show for the first time the inhibition of both microRNA-33a and microRNA-33b (miR-33a/b) with chemically modified anti-miR oligonucleotides markedly suppress triglyceride levels and cause a sustained increase in high density lipoprotein cholesterol (HDL-C) "good" cholesterol... -
Monitoring Cholesteral Drugs Via MRI
Posted: October 17th, 2011, 3:00am CDT
MRI scanning could become a powerful new tool for assessing how well cholesterol drugs are working, according to Loyola University Health System cardiologist Binh An P. Phan, MD. Phan is co-author of an MRI study of patients who had recently begun taking cholesterol medications... -
Monitoring Cholesterol Drugs Via MRI
Posted: October 17th, 2011, 3:00am CDT
MRI scanning could become a powerful new tool for assessing how well cholesterol drugs are working, according to Loyola University Health System cardiologist Binh An P. Phan, MD. Phan is co-author of an MRI study of patients who had recently begun taking cholesterol medications... -
Gut Bacteria Influence Statin Treatment Response
Posted: October 16th, 2011, 4:00pm CDT
Bacteria that exist in our gut may affect how people respond to statins; medications used to control blood cholesterol levels. To date, doctors have not been able to properly explain why some patients on cholesterol-lowering medications respond well, while others don't... -
Cholesterol Lowering By Statins May Be Affected By Gut Bacteria
Posted: October 15th, 2011, 2:00am CDT
Statins can be effective at lowering cholesterol, but they have a perplexing tendency to work for some people and not others. Gut bacteria may be the reason. A research team led by a Duke University scientist has identified three bile acids produced by gut bacteria that were evident in people who responded well to a common cholesterol-lowering drug called simvastatin... -
A New Use For Statins?
Posted: October 11th, 2011, 2:00am CDT
Older patients who happened to have been taking cholesterol-lowering statin drugs when admitted to the hospital with serious head injuries were 76 percent more likely to survive than those not taking the drugs, according to results of a Johns Hopkins study. Those taking statins also had a 13 percent greater likelihood of achieving good, functional recovery after one year... -
Diabetes Patients Who Raise Their 'Good' Cholesterol Levels Reduce Their Risk Of Heart Attack And Stroke
Posted: October 10th, 2011, 2:00am CDT
Increasing levels of high-density lipoproteins, better known as HDL or "good" cholesterol, reduced the risk for heart attack and stroke among patients with diabetes. That's according to a new study appearing online in The American Journal of Cardiology... -
Sitagliptin And Simvastatin Combination - Juvisync - Approved By FDA For Diabetes With High Cholesterol
Posted: October 7th, 2011, 2:00pm CDT
The first single tablet for both diabetes type 2 and high cholesterol, Juvisync (sitagliptin and simvastatin), has been approved by the FDA (Food and Drug Administration). Sitagliptin and simvastatin are previously approved medications to separately treat elevated sugar and high cholesterol respectively. The new tablet, Juvisync, is an FDC (fixed-dose combination) of the two medications... -
Animal Study Warns Of Possible Cardiovascular Risk With NSAID Use
Posted: September 28th, 2011, 2:00am CDT
A new study from Rhode Island Hospital researchers suggests that controlling cholesterol may be important for heart health in patients who are taking non-steroidal anti-inflammatory drugs (NSAIDs) such as naproxen. The findings are based on a study on the safety of NSAID medications in clinically relevant animal models when high cholesterol is a factor... -
Progression Of Clogged Arteries Reduced By Soy Proetein In Women Within 5 Years Of Menopause
Posted: September 25th, 2011, 2:00am CDT
A new study published in the November 2011 issue of Stroke reveals some promising data on the positive effects of soy protein reducing the progression of clogged arteries in women who were within five years of menopause... -
Treating Glioblastoma By Starving Cancer Cells Of Cholesterol
Posted: September 18th, 2011, 2:00am CDT
A new study suggests that blocking cancer cells' access to cholesterol may offer a new strategy for treating glioblastoma, the most common and deadly form of brain cancer, and perhaps other malignancies. The potential treatment could be appropriate for tumors with a hyperactive PI3K signaling pathway, which accounts for up to 90 percent of glioblastomas cases... -
Stopping Brain Cancer Cells Feeding On Cholesterol Could Be A New Treatment
Posted: September 16th, 2011, 4:00am CDT
Brain tumor cells feed on cholesterol, and blocking their access to it may offer a new way of treating glioblastoma, the most deadly form of brain cancer, and perhaps other cancers too, say US researchers in a new study published online this week in the journal Cancer Discovery...