My Health News » Medical News Today - Cholesterol » September 2008

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Medical News Today - Cholesterol (18 unread)

• Statins Not Linked To Higher Risk Of ALS Says FDA

  Posted: September 30th, 2008, 6:00am EDT

  A new analysis by the US Food and Drug Administration (FDA) of data from over 40 clinical trials did not show a link between statins, drugs used to lower cholesterol, and higher risk of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease often referred to as "Lou Gehrig's Disease". The FDA said there is no need to change prescribing practice.

• New Model Created For Protein-Cholesterol Interactions In Brain And Muscle Tissue

  Posted: September 29th, 2008, 4:00am EDT

  Biophysicists at the University of Pennsylvania have used 3,200 computer processors and long-established data on cholesterol's role in the function of proteins to clarify the mysterious interaction between cholesterol and neurotransmitter receptors.

• Researchers Study How Pistachios May Improve Heart Health

  Posted: September 29th, 2008, 3:00am EDT

  Going green may be heart healthy if the green you choose is pistachio nuts, according to researchers at Penn State who conducted the first study to investigate the way pistachios lower cholesterol. "We investigated mechanisms of action to explain the cholesterol-lowering effects of the pistachio diets," says Sarah K. Gebauer, recent Penn State Ph.D. recipient, currently a post-doctoral research associate, USDA Beltsville Human Nutrition Research Center.

• Medco Study: Medicare Coverage Gap Leads To Drop Off In Drug Therapy For High Cholesterol Patients; Brand Medication Users At Greatest Risk

  Posted: September 26th, 2008, 3:00am EDT

  Seniors battling high cholesterol are more likely to stop taking their medications once they reach the Medicare Coverage Gap, a result that may put them at higher risk for heart attack and stroke. New research by Medco Health Solutions, Inc.

• Galmed Medical Research Initiates Phase I Study Of Aramchol, Leading Drug Candidate For Fatty Liver Disease

  Posted: September 24th, 2008, 5:00am EDT

  Galmed Medical Research Ltd., a leading biopharmaceutical company that develops innovative proprietary drugs for the treatment of cholesterol and liver diseases, announced today that it has started its Phase-I study in healthy human volunteers of its novel drug, Aramchol, developed for Fatty Liver Disease.

• Inhibiting Cholesterol-Associated Protein Reduces High-Risk Blockages In Arteries

  Posted: September 23rd, 2008, 7:00am EDT

  Using the drug darapladib, researchers at the University of Pennsylvania School of Medicine and colleagues have inhibited a cholesterol-and immune system-associated protein, thereby reducing the development of heart-disease plaques that may cause death, heart attacks, and strokes in a pig model of atherosclerosis and diabetes. The study appeared online this week in Nature Medicine.

• Cholesterol Harms More Than The Heart: Prostate Also At Risk

  Posted: September 19th, 2008, 6:00am EDT

  Heart health isn't the only reason to pay attention to cholesterol levels: Research has shown that cholesterol plays an important role in prostate health as well. September has been designated both National Prostate Health Month and National Cholesterol Education Month, and the American Urological Association (AUA) and the AUA Foundation are urging men to decrease their risk of developing prostate cancer by managing their cholesterol.

• Human Skin Cells Turned Into Insulin-Producing Cells

  Posted: September 19th, 2008, 3:00am EDT

  Researchers at the University of North Carolina at Chapel Hill School of Medicine have transformed cells from human skin into cells that produce insulin, the hormone used to treat diabetes. The breakthrough may one day lead to new treatments or even a cure for the millions of people affected by the disease, researchers say.

• Lipid-Lowering Therapies And Cardiovascular Disease Prevention

  Posted: September 14th, 2008, 3:00am EDT

  Strategies for cardiovascular disease (CVD) prevention using lipid-lowering medications can be improved by adopting the absolute-risk approach, according to a research paper in the latest issue of the Medical Journal of Australia. Lipid-lowering medication reduces blood cholesterol levels, an important risk factor for CVD.

• eHealthMe.com Offers New Look At Statin Side Effects Study, More Research May Be Needed

  Posted: September 7th, 2008, 3:00am EDT

  In 2004, the FDA sponsored a study on occurrences of rhabdomyolysis, a sometimes deadly side effect of cholesterol-lowering statins, generally believed to be rare after the withdrawal of cerivastatin. The FDA study looked at patients using statins for a period of one year, with results showing that only 0.44 in 10,000 patients will develop this sometimes life-threatening condition. The creators of eHealthMe.

• Elderly Benefit From Cholesterol Drugs To Lower Risk Of Stroke

  Posted: September 6th, 2008, 6:00am EDT

  Elderly people who take a cholesterol drug after a stroke or mini-stroke lower their risk of having another stroke just as much as younger people in the same situation, according to research published in the September 3, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology.

• New Research Supports Need For Healthy Diet In Conjunction With Statins To Effectively Lower Cholesterol

  Posted: September 5th, 2008, 4:00am EDT

  New research commissioned by Flora pro.activ revealed that two thirds of GPs polled feel that it is very important for patients on cholesterol-lowering medication to also ensure they eat a healthy diet to improve heart health. According to recent NICE guidance on the management of Familial Hypercholesterolaemia (FH), first-line treatment for FH should be statins.

• Cholesterol In The News: Answers And More Questions

  Posted: September 4th, 2008, 4:00am EDT

  Understanding cholesterol is more than figuring out what's good and bad. Although much is known about this waxy substance that's in all body cells and its relationship with heart disease, much is still uncertain. Doctors suspect that the relationship may be more complicated than previously believed. The September issue of Mayo Clinic Women's HealthSource provides an overview of cholesterol and recent news about cholesterol medications.

• Lipitor 80 Mg Provided Sustained Risk Reduction Of Cardiovascular Events In Patients With Heart Disease During The Five-Year TNT Trial

  Posted: September 3rd, 2008, 6:00am EDT

  Pfizer announced that in patients with established heart disease, Lipitor® (atorvastatin calcium) 80 mg not only significantly reduced the relative risk of suffering a first cardiovascular event by 19 percent compared to Lipitor 10 mg but also provided a sustained reduction in the risk of a subsequent second, third, fourth, and fifth cardiovascular event, according to a subanalysis of the five-year Treating to New Targets (TNT) study.

• Ezetimibe And Cancer Link Still Not Clear Say Experts

  Posted: September 3rd, 2008, 5:00am EDT

  The link between cholesterol-lowering drug ezetimibe (marketed as Vytorin) and cancer is still not clear, wrote the editors of the leading medical journal New England Journal of Medicine (NEJM). More time is needed to assess the drug, they said, and in the meantime patients and doctors will have to live with the uncertainty.

• Survey Among European Cardiologists Points To A Gap In Cardiovascular Disease Management

  Posted: September 3rd, 2008, 4:00am EDT

  Cardiologists in Europe agree that reducing LDLcholesterol (LDL-C or "bad" cholesterol) is the most important consideration when treating dyslipidaemia (abnormal blood lipids). A majority of cardiologists also agree that in addition to lowering LDL-C, raising HDL-cholesterol (HDL-C or "good" cholesterol) and reducing triglycerides are important factors in choosing dyslipidaemia treatment.

• Patients Who Discontinue Statin Therapy May Be More Likely To Die, New Observational Study Shows

  Posted: September 2nd, 2008, 4:00am EDT

  The results of a new observational study presented recently at the showed that patients who stop taking their prescribed statins have a four-fold increased risk of death during the first year following an acute coronary syndrome. The study included 2,234 patients who were prescribed statin therapy after an acute coronary syndrome. Patients were followed for one year after discharge from the hospital.

• Issues On Cholesterol: Diet, Statins And Genetics

  Posted: September 1st, 2008, 8:00am EDT

  Genetic lipoprotein disorders are frequently seen in patients with premature coronary artery disease (CAD). An example of strong genetic predisposition is the disorder: familial hypercholesterolemia, where a single gene defect (the low density lipoprotein receptor) contributes to most of the familial expression of CAD.