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Posted: September 5th, 2008, 6:00am EDT
Biodel Inc. (Nasdaq: BIOD) announced that it will report results of its two pivotal Phase III clinical trials of VIAject™ in patients with Type 1 and Type 2 diabetes next week at the 44th Annual Meeting of the European Association for the Study of Diabetes in Rome. Two posters summarizing these results, #677 by Flacke et al.
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Posted: September 5th, 2008, 6:00am EDT
Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that Merck's Januvia is currently prescribed most often as a third- or later-line of therapy for the treatment of type 2 diabetes.
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Posted: September 5th, 2008, 6:00am EDT
OSI Pharmaceuticals, Inc. (Nasdaq: OSIP) announced that it has initiated a first-in-human clinical study for its G-protein coupled receptor GPR119 agonist, PSN821, which the Company is developing for the treatment of type 2 diabetes. Discovered by OSI's diabetes and obesity research team, PSN821 demonstrated both effective glucose lowering and substantial reductions of body weight in pre-clinical studies.
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Posted: September 5th, 2008, 5:00am EDT
Serum microRNAs (miRNAs) can serve as biomarkers for the detection of diseases including cancer and diabetes, according to research published online this week in Cell Research. The findings pave the way for a revolutionary non-invasive diagnostic tool. miRNAs are a class of naturally occurring small non-coding RNAs that have been linked with cancer development.
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Posted: September 5th, 2008, 4:00am EDT
Dr. Marcus Conrad of the Institute of Clinical Molecular Biology and Tumor Genetics at the Helmholtz Zentrum München has decrypted the molecular mechanism through which the death of cells is caused by oxidative stress. This knowledge opens novel perspectives to systematically explore the benefit of targeted therapeutic interventions in the cure of ageing and stress-related degenerative diseases.
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Posted: September 5th, 2008, 3:00am EDT
A recent study (doi:10.1016/j.clim.2008.06.009) published in Clinical Immunology, the official journal of the Clinical Immunology Society (CIS), describes a new method enabling the detection of multiple parameters of single human cells. The report demonstrates the characterization of specific blood cells from an individual with type 1 diabetes, providing information about the role these cells might play in the development of the disease and during therapy.